Table 4 Clinical, laboratory variables and outcomes in each group of neonates admitted within 3Â days of life
From: Early-onset neonatal sepsis and antibiotic use in Indonesia: a descriptive, cross-sectional study
Clinical and laboratory variables | Received antibiotic within 3d of life (n = 1,039) | ||||
|---|---|---|---|---|---|
EOS | Non-EOS (n = 797) | ||||
Culture proven (n = 83) | Culture negative (n = 112) | Absence of culture facility (n = 47) | Total (n = 242) | ||
Temperature instability | 68 (81.9%) | 81 (72.3%) | 40 (85.1%) | 189 (78.1%) | 219 (27.5%) |
Increased oxygen requirement or ventilatory support | 65 (78.3%) | 88 (78.6%) | 44 (93.6%) | 197 (81.4%) | 355 (44.5%) |
Glucose intolerance | 64 (77.1%) | 56 (50.0%) | 11 (23.4%) | 131 (54.1%) | 121 (15.2%) |
Lethargy | 62 (74.7%) | 63 (56.3%) | 30 (63.8%) | 155 (64.0%) | 133 (16.7%) |
Ileus/feeding intolerance or abdominal distension | 52 (62.7%) | 48 (42.9%) | 21 (44.7%) | 121 (50.0%) | 81 (10.2%) |
Increase in apnoeic or bradycardic episodes or tachycardia | 24 (28.9%) | 38 (33.9%) | 13 (27.7%) | 75 (31.0%) | 56 (7.0%) |
Hypotension or prolonged capillary refill | 5 (6.0%) | 15 (13.4%) | 12 (25.5%) | 32 (13.2%) | 31 (3.9%) |
Base deficit > 10 mmol/L | 5 (6.0%) | 34 (30.4%) | 0 (0.0%) | 39 (16.1%) | 62 (7.8%) |
Outcomes | |||||
 14-d mortality | 12 (14.5%) | 27 (24.1%) | 3 (6.4%) | 42 (17.4%) | 78 (9.8%) |
 28-d mortality | 21 (25.3%) | 28 (25.0%) | 3 (6.4%) | 52 (21.5%) | 81 (10.2%) |