Table 1 Repeated measures ANOVA for change in depressive symptoms, anxiety symptoms and QoL over time*

Factor scores

Depressive symptoms

4.22

0.0158

5.40 ± 0.34^a

4.21 ± 0.44^b

4.00 ± 0.45^b

Total Anxiety symptoms

20.83

 < 0.0001

5.66 ± 0.43^a

2.65 ± 0.54^b

2.00 ± 0.54^b

  Fear Factor

8.39

0.0003

1.56 ± 0.17^a

0.84 ± 0.22^b

0.56 ± 0.22^b

  Nervous Factor

16.68

 < 0.0001

1.69 ± 0.14^a

0.61 ± 0.17^b

0.88 ± 0.18^b

  Panic Factor

8.53

0.0003

1.07 ± 0.12^a

0.63 ± 0.16^a,b

0.25 ± 0.16^b

  Somatic Factor

20.43

 < 0.0001

2.32 ± 0.69^a

1.56 ± 0.70^b

1.32 ± 0.71^b

Total QoL

9.85

 < 0.0001

34.24 ± 1.24^a

36.05 ± 1.58^a

27.25 ± 1.59^b

  Physical Health

22.14

 < 0.0001

48.04 ± 1.45^a

44.15 ± 1.45^a

35.91 ± 1.46^b

  Role Physical

6.21

0.0023

28.25 ± 2.34^a

29.25 ± 2.98^a

16.74 ± 2.99^b

  Role Emotional

4.18

0.0163

40.65 ± 2.54^a,b

43.89 ± 3.22^a

31.89 ± 3.24^b

  GHV

24.46

 < 0.0001

19.74 ± 0.72^a

26.95 ± 0.91^b

24.46 ± 0.92^b