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Table 4 Expert perspectives on the implementation barriers for introducing of TACTs in Southeast Asia

From: Expert perspectives on the introduction of Triple Artemisinin-based Combination Therapies (TACTs) in Southeast Asia: a Delphi study

Implementation barriers

Explanation

n

Intensified prescriber training

Intensifying training requirements for correct TACTs prescription

27

Donor funder support

Obtaining support by donor funders to cover TACTs implementation costs and potential price increases

24

National policy support

Obtaining support from national malaria control programs and other national decision makers

24

WHO and global policy support

Obtaining support from the WHO and other global decision makers

19

Availability of fixed-dose combination (FDC) TACTs

Ensuring timely development and production of fixed-dose combination (FDC) for TACTs

17

Community acceptance

Ensuring community acceptance by providing clear communication and tackling potential misconceptions about TACTs

12

Collecting safety and efficacy data

Collecting sufficient efficacy and safety data to support the introduction of TACTs

11

Supply chain logistics

Adapting import, procurement and supply routes for the introduction of TACTs

11

Regulatory approval

Obtaining timely regulatory approval for introducing TACTs in Southeast Asia

11

Set up surveillance systems

Setting up surveillance systems to monitor drug resistance and adherence to TACTs

9

Private sector engagement

Engaging the (informal) private sector in TACTs deployment and creating demand beyond official programs

5

Set up pharmacovigilance systems

Setting up a pharmacovigilance system for TACTs

4

Stockpile management

Managing stockpiles for countries that still have ACT stocks or contract deals with ACT producers

3