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Table 6 HR of resolution and incident NAFLD according to temporal PA change in BMI change ≤0 group

From: Effect of physical activity on the development and the resolution of nonalcoholic fatty liver in relation to body mass index

 

Person-years

Events (No.)

Event rate (per 100,000 person-years)

Age- and sex-adjusted HR (95% CI)

Multivariable-adjusted HR (95% CI)

Model 1

Model 2

Model 3

Resolution of NAFLD

 Inactive→Inactive

9984.5

679

6.80

1.00

1.00

1.00

1.00

 Active or HEPA→Inactive

6053.5

381

6.29

0.97 (0.86–1.10)

1.04 (0.92–1.18)

1.01 (0.89–1.15)

1.04 (0.92–1.18)

 Inactive- → Active or HEPA

7373.8

502

6.80

1.05 (0.94–1.18)

1.05 (0.94–1.18)

1.08 (0.97–1.22)

1.00 (0.89–1.13)

 Active or HEPA→Active or HEPA

12,075.7

877

7.26

1.21 (1.09–1.34)

1.26 (1.14–1.40)

1.24 (1.12–1.38)

1.18 (1.07–1.31)

Incident NAFLD

 Inactive→Inactive

25,070.9

650

2.59

1.00

1.00

1.00

1.00

 Active or HEPA→Inactive

14,209.1

452

3.18

1.04 (0.92–1.17)

1.02 (0.91–1.15)

1.02 (0.90–1.15)

1.00 (0.89–1.13)

 Inactive- → Active or HEPA

14,575.9

450

3.08

1.03 (0.91–1.16)

1.03 (0.91–1.16)

0.94 (0.83–1.06)

0.99 (0.88–1.12)

 Active or HEPA→Active or HEPA

25,353.3

860

3.39

0.92 (0.83–1.02)

0.90 (0.82–1.00)

0.89 (0.80–0.99)

0.93 (0.83–1.03)

  1. Model 1: adjustment for age, sex, center, year of screening exam, smoking status, alcohol intake, education level
  2. Model 2: model 1 adjustments plus adjustment for waist circumference
  3. Model 3: model 2 adjustments plus adjustment for waist circumference changes
  4. The reference group was persistently inactive group
  5. Abbreviations: BMI Body mass index, CI Confidence interval, HEPA Health-enhancing physical activity, HR Hazard ratio, NAFLD Non-alcoholic fatty liver disease, PA Physical activity