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Table 5 HR of resolution and incident NAFLD according to temporal PA change in BMI change >0 group

From: Effect of physical activity on the development and the resolution of nonalcoholic fatty liver in relation to body mass index

 

Person-years

Events (No.)

Event rate (per 100,000 person-years)

Age- and sex-adjusted HR (95% CI)

Multivariable-adjusted HR (95% CI)

Model 1

Model 2

Model 3

Resolution of NAFLD

 Inactive→Inactive

18,027.0

407

2.25

1.00

1.00

1.00

1.00

 Active or HEPA→Inactive

12,962.8

268

2.06

0.98 (0.84–1.15)

1.04 (0.89–1.22)

1.04 (0.89–1.21)

1.07 (0.91–1.25)

 Inactive- → Active or HEPA

9545.3

237

2.48

1.17 (0.99–1.37)

1.17 (0.99–1.37)

1.19 (1.02–1.40)

1.16 (0.99–1.36)

Active or HEPA→Active or HEPA

19,751.9

424

2.14

1.08 (0.94–1.24)

1.12 (0.98–1.29)

1.11 (0.97–1.28)

1.10 (0.96–1.27)

Incident NAFLD

 Inactive→Inactive

63,556.4

3448

5.45

1.00

1.00

1.00

1.00

 Active or HEPA→Inactive

40,517.9

2617

6.45

0.99 (0.94–1.05)

1.04 (0.98–1.09)

1.03 (0.98–1.08)

0.99 (0.94–1.04)

 Inactive- → Active or HEPA

30,474.9

1768

5.80

0.90 (0.85–0.96)

0.91 (0.86–0.96)

0.89 (0.84–0.94)

0.90 (0.85–0.96)

 Active or HEPA→Active or HEPA

59,022.7

3821

6.47

0.87 (0.83–0.92)

0.90 (0.86–0.94)

0.89 (0.85–0.94)

0.89 (0.85–0.93)

  1. Model 1: adjustment for age, sex, center, year of screening exam, smoking status, alcohol intake, education level
  2. Model 2: model 1 adjustments plus adjustment for waist circumference
  3. Model 3: model 2 adjustments plus adjustment for waist circumference changes
  4. The reference group was persistently inactive group
  5. Abbreviations: BMI Body mass index, CI Confidence interval, HEPA Health-enhancing physical activity, HR Hazard ratio, NAFLD Non-alcoholic fatty liver disease, PA Physical activity