Skip to main content

Table 2 Statistical analyses to be completed by the endpoint

From: Protocol for a cluster randomised controlled trial of secondary distribution of hepatitis C self-testing within the context of a house-to-house hepatitis C micro-elimination programme in Karachi, Pakistan

Endpoint Statistical analysis method
1.1 The number and estimate of the proportion of participants who report completing HCV antibody testing in the intervention group
1.2 To assess whether the proportion of participants who report completing HCV antibody testing in the intervention group is greater than that of participants in the control group, by a margin of 20%
Test of proportions, comparing the proportion of individuals reporting HCV test results in the intervention versus control groups and between intervention groups
2.1 The number and estimate of the proportion of HCV antibody-positive individuals made aware of their status in the intervention versus the control group Descriptive statistics; statistical tests comparing the number of individuals in the intervention versus the control group and between intervention groups
2.2 The number and estimate of the proportion of HCV antibody-positive individuals who are referred to and complete HCV RNA confirmatory testing in the intervention versus the control group
2.3 The number and estimate of the proportion of HCV RNA-positive individuals who begin treatment in the intervention versus the control group
2.4 Analysis of survey responses using proportions and means Descriptive statistics for survey responses (e.g. proportions, means)
2.5 Cost per test completed and cost per person diagnosed (serology, RNA) in the intervention versus the control group Ingredients-based cost calculation approach