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Table 2 Discounted cost of HPV vaccination for target population at the national and provincial levels (US$)

From: Human papillomavirus vaccination at the national and provincial levels in China: a cost-effectiveness analysis using the PRIME model

Province and region

Vaccination costs

Treatment cost savings

Net cost

Domestic bivalent vaccine

Imported bivalent vaccine

Imported quadrivalent vaccine

Imported 9-valent vaccine

Domestic bivalent vaccine

Imported bivalent vaccine

Imported quadrivalent vaccine

Imported 9-valent vaccine

Domestic bivalent vaccine

Imported bivalent vaccine

Imported quadrivalent vaccine

Imported 9-valent vaccine

Heilongjiang

22,040,361

38,075,322

52,002,738

115,770,557

2,768,229

2,768,229

2,768,229

5,092,636

19,272,132

35,307,093

49,234,509

110,677,921

Jilin

15,900,744

27,402,289

37,392,137

83,165,994

1,985,593

1,985,593

1,985,593

3,652,832

13,915,151

25,416,696

35,406,543

79,513,162

Liaoning

26,085,902

44,687,292

60,843,820

135,014,094

3,211,290

3,211,290

3,211,290

5,907,720

22,874,612

41,476,002

57,632,530

129,106,374

Hebei

45,768,030

78,219,994

106,406,656

235,901,638

5,602,413

5,602,413

5,602,413

10,306,583

40,165,617

72,617,581

100,804,244

225,595,055

Shanxi

22,481,573

38,422,202

52,267,686

115,876,523

2,751,944

2,751,944

2,751,944

5,062,665

19,729,629

35,670,258

49,515,742

110,813,858

Shandong

60,660,497

104,038,235

141,714,649

314,612,022

7,488,607

7,488,607

7,488,607

13,776,574

53,171,890

96,549,628

134,226,042

300,835,449

Shaanxi

23,037,107

39,605,128

53,995,543

119,983,034

2,860,255

2,860,255

2,860,255

5,261,920

20,176,852

36,744,873

51,135,288

114,721,113

Henan

56,310,467

97,516,746

133,307,105

297,051,359

7,113,732

7,113,732

7,113,732

13,086,924

49,196,735

90,403,014

126,193,373

283,964,435

Anhui

38,920,069

66,131,219

89,765,889

198,553,960

4,697,654

4,697,654

4,697,654

8,642,120

34,222,415

61,433,565

85,068,236

189,911,840

Jiangsu

47,964,187

82,459,477

112,420,902

249,809,742

5,955,167

5,955,167

5,955,167

10,955,541

42,009,021

76,504,311

106,465,735

238,854,202

Hubei

35,932,757

61,267,845

83,273,032

184,445,344

4,373,776

4,373,776

4,373,776

8,046,285

31,558,981

56,894,069

78,899,256

176,399,059

Sichuan

51,203,365

87,002,439

118,096,285

261,218,215

6,180,248

6,180,248

6,180,248

11,369,600

45,023,117

80,822,191

111,916,037

249,848,615

Zhejiang

35,566,628

60,572,516

82,291,772

182,188,048

4,316,944

4,316,944

4,316,944

7,941,749

31,249,684

56,255,572

77,974,829

174,246,299

Hunan

43,503,767

74,791,174

101,966,341

226,578,816

5,401,367

5,401,367

5,401,367

9,936,736

38,102,400

69,389,807

96,564,974

216,642,080

Jiangxi

28,312,597

48,218,382

65,507,863

145,029,669

3,436,477

3,436,477

3,436,477

6,321,980

24,876,120

44,781,905

62,071,387

138,707,689

Yunnan

29,453,709

50,220,618

68,258,043

151,187,989

3,585,139

3,585,139

3,585,139

6,595,458

25,868,570

46,635,479

64,672,904

144,592,530

Guizhou

21,964,296

37,450,649

50,901,564

112,744,316

2,673,519

2,673,519

2,673,519

4,918,383

19,290,777

34,777,130

48,228,045

107,825,933

Fujian

23,613,620

40,596,264

55,346,805

122,985,854

2,931,834

2,931,834

2,931,834

5,393,611

20,681,786

37,664,430

52,414,971

117,592,244

Guangdong

69,454,096

118,700,739

161,474,683

357,987,007

8,501,797

8,501,797

8,501,797

15,640,514

60,952,298

110,198,942

152,972,886

342,346,494

Beijing

12,982,978

22,188,599

30,184,285

66,917,977

1,589,232

1,589,232

1,589,232

2,923,658

11,393,746

20,599,367

28,595,053

63,994,319

Tianjin

9,415,446

16,091,497

21,890,086

48,529,921

1,152,534

1,152,534

1,152,534

2,120,281

8,262,912

14,938,963

20,737,552

46,409,640

Shanghai

14,637,955

25,017,042

34,031,961

75,448,581

1,791,816

1,791,816

1,791,816

3,296,361

12,846,139

23,225,227

32,240,146

72,152,219

Chongqing

18,834,957

32,189,942

43,789,623

97,080,559

2,305,566

2,305,566

2,305,566

4,241,466

16,529,391

29,884,376

41,484,057

92,839,093

Inner Mongolia

15,959,188

26,814,737

36,243,495

79,807,048

1,874,070

1,874,070

1,874,070

3,447,663

14,085,118

24,940,667

34,369,424

76,359,385

Xinjiang

14,909,612

25,694,237

35,061,393

77,981,887

1,861,826

1,861,826

1,861,826

3,425,135

13,047,785

23,832,411

33,199,567

74,556,752

Ningxia

4,105,085

7,074,432

9,653,504

21,470,997

512,619

512,619

512,619

943,053

3,592,466

6,561,812

9,140,885

20,527,943

Tibet

2,071,621

3,570,095

4,871,618

10,835,334

258,692

258,692

258,692

475,912

1,812,929

3,311,403

4,612,926

10,359,422

Guangxi

34,042,388

58,385,772

79,529,600

176,558,372

4,202,571

4,202,571

4,202,571

7,731,330

29,839,817

54,183,201

75,327,029

168,827,042

Qinghai

3,591,889

6,190,024

8,446,674

18,786,893

448,534

448,534

448,534

825,161

3,143,355

5,741,489

7,998,140

17,961,732

Gansu

15,735,046

27,051,509

36,880,601

81,952,195

1,953,641

1,953,641

1,953,641

3,594,058

13,781,405

25,097,868

34,926,959

78,358,138

Hainan

5,615,027

9,653,289

13,160,786

29,244,365

697,154

697,154

697,154

1,282,527

4,917,873

8,956,135

12,463,632

27,961,838

National

840,791,627

1,439,992,866

1,960,438,493

4,312,777,862

103,444,361

103,444,361

103,444,361

188,681,737

737,347,266

1,336,548,506

1,856,994,132

4,124,096,125