Table 2 Regression models of drug consumption and mortality in the cohort (N = 232,507)

Gender

 Men (ref.)

1

-

1

-

1

-

1

-

 Women

1.11

[1.07; 1.15]

0.79

[0.77; 0.80]

0.77

[0.72; 0.82]

0.80

[0.73; 0.89]

Deprivation Index

 Very Low (ref.)

1

-

1

-

1

-

1

-

 Medium Low

0.99

[0.94; 1.04]

1.04

[1.01; 1.07]

1.08

[0.99; 1.18]

1.01

[0.89; 1.16]

 Medium High

0.92

[0.88; 0.97]

1.04

[1.01; 1.07]

1.18

[1.08; 1.28]

1.12

[0.98; 1.27]

 Very High

0.90

[0.86; 0.94]

1.06

[1.03; 1.09]

1.24

[1.14; 1.35]

1.15

[1.02; 1.31]

Age class

 30–34 (ref.)

1

-

1

-

1

-

1

-

 35–39

1.43

[1.18; 1.73]

1.05

[0.89; 1.24]

0.79

[0.20; 3.19]

1.57

[0.18; 14.10]

 40–44

1.99

[1.67; 2.37]

1.07

[0.92; 1.24]

0.70

[0.20; 2.46]

1.08

[0.13; 8.78]

 45–49

2.37

[2.00; 2.80]

1.14

[0.99; 1.31]

0.63

[0.19; 2.11]

0.54

[0.07; 4.44]

 50–54

3.14

[2.66; 3.71]

1.21

[1.05; 1.40]

1.05

[0.33; 3.35]

1.11

[0.15; 8.21]

 55–59

3.76

[3.18; 4.44]

1.31

[1.13; 1.50]

1.45

[0.46; 4.58]

1.62

[0.22; 11.82]

 60–64

4.11

[3.48; 4.86]

1.49

[1.29; 1.71]

1.84

[0.58; 5.81]

1.75

[0.24; 12.74]

 65–69

4.70

[3.97; 5.57]

1.58

[1.37; 1.82]

2.88

[0.92; 9.04]

2.56

[0.35; 18.48]

 70–74

4.68

[3.95; 5.54]

1.84

[1.59; 2.12]

3.99

[1.28; 12.51]

3.48

[0.48; 25.04]

 75–79

4.22

[3.56; 5.00]

1.90

[1.65; 2.19]

7.06

[2.26; 22.06]

6.63

[0.93; 47.46]

 80–84

2.73

[2.30; 3.23]

1.87

[1.62; 2.16]

13.97

[4.47; 43.65]

15.58

[2.18; 111.36]

 85–89

1.24

[1.05; 1.47]

1.93

[1.67; 2.24]

32.71

[10.47; 102.14]

36.13

[5.06; 258.03]

 90–94

0.50

[0.42; 0.59]

2.10

[1.79; 2.46]

79.50

[25.44; 248.44]

88.73

[12.42; 633.90]

 95–99

0.26

[0.21; 0.32]

2.77

[2.25; 3.41]

198.86

[63.34; 624.31]

170.33

[23.76; 1,221.25]

Citizenship

 Italian (ref.)

1

-

1

-

1

-

1

-

 Other

0.59

[0.56; 0.63]

0.96

[0.92; 1.01]

0.77

[0.56; 1.04]

0.87

[0.55; 1.39]

Hospital admission

 No (ref.)

1

-

1

-

1

-

1

-

 Yes

1.50

[1.42; 1.59]

1.07

[1.04; 1.10]

5.26

[4.92; 5.62]

2.65

[2.39; 2.94]

First-aid access

 No (ref.)

1

-

1

-

1

-

1

-

 Yes

1.74

[1.67; 1.81]

0.97

[0.95; 0.99]

2.34

[2.18; 2.52]

1.94

[1.74; 2.17]

80% Compliance

 No (ref.)

N.A

N.A

1

-

1

-

 Yes

1.39

[1.27; 1.51]

1.55

[1.34; 1.78]