Fig. 2

Age-adjusted marginal means of ACC/AHA CVD risk score (A), systolic blood pressure (B), total cholesterol (C), HDL- cholesterol (D), fasting plasma glucose (E), and current smoking (F) in each phase in men separated by diabetes status. Dash lines show the diabetic group, and solid lines show the non-diabetic group. Models for assessment of time trend were fitted separately for diabetic and non-diabetic subjects, and age-adjusted marginal means and p-values for trend were reported. Meanwhile, the interaction of diabetes status with time was assessed by fitting a model including diabetes status, the follow-up time and their cross-product in a pooled model including both diabetic and non-diabetic participants, and p-values for the cross-product term were reported as p for trend