Table 3 Incidence rates and hazard ratios of stroke for total physical activity

Male

21.8–34.5

 > 34.5–45.8

 > 45.8–140.7

Female

22.0–31.7

 > 31.7–38.2

 > 38.2–128.9

Total

 Stroke, ischemic and hemorrhagic

  Number of events

680

621

578

  Person-years (py)

186,105

188,926

189,091

  Event rate per 100,000 py^a

365.3

328.7

305.7

  HR (95% CI)^a

1.00 (0.99–1.00)

1.00 (reference)

1.05 (0.94–1.17)

1.00 (0.89–1.12)

  HR (95% CI)^b

1.00 (0.99–1.00)

1.00 (reference)

1.04 (0.92–1.17)

0.99 (0.88–1.12)

  HR (95% CI)^c

1.00 (0.99–1.00)

1.00 (reference)

1.09 (0.96–1.23)

1.04 (0.92–1.19)

 Stroke, ischemic

  Number of events

468

397

408

  Person-years

186,105

188,926

189,091

  Event rate per 100,000 py^a

251.5

210.1

215.8

  HR (95% CI)^a

1.00 (0.99–1.00)

1.00 (reference)

0.99 (0.86–1.13)

1.03 (0.90–1.18)

  HR (95% CI)^b

1.00 (0.99–1.00)

1.00 (reference)

0.97 (0.84–1.12)

1.02 (0.88–1.18)

  HR (95% CI)^c

1.00 (0.99–1.00)

1.00 (reference)

1.02 (0.87–1.19)

1.07 (0.92–1.25)

 Stroke, hemorrhagic

  Number of events

114

114

84

  Person-years

186,105

188,926

189,091

  Event rate per 100,000 py^a

61.3

60.3

44.4

  HR (95% CI)^a

1.00 (0.99–1.00)

1.00 (reference)

1.11 (0.85–1.44)

0.83 (0.63–1.11)

  HR (95% CI)^b

1.00 (0.99–1.00)

1.00 (reference)

1.08 (0.81–1.42)

0.85 (0.63–1.14)

  HR (95% CI)^c

1.00 (0.99–1.00)

1.00 (reference)

1.15 (0.86–1.54)

0.93 (0.68–1.27)

Male

 Stroke, ischemic and hemorrhagic

  Number of events

254

289

285

  Person-years

61,492

61,944

62,055

  Event rate per 100,000 py^a

413.1

466.6

459.3

  HR (95% CI)^a

1.00 (0.99–1.00)

1.00 (reference)

1.13 (0.95–1.34)

1.15 (0.97–1.37)

  HR (95% CI)^b

1.00 (0.99–1.00)

1.00 (reference)

1.10 (0.92–1.32)

1.12 (0.93–1.35)

  HR (95% CI)^c

1.00 (0.99–1.00)

1.00 (reference)

1.13 (0.94–1.37)

1.14 (0.94–1.39)

 Stroke, ischemic

  Number of events

178

194

205

  Person-years

61,492

61,944

62,055

  Event rate per 100,000 py^a

289.5

313.2

330.4

  HR (95% CI)^a

1.00 (0.99–1.00)

1.00 (reference)

1.08 (0.88–1.33)

1.18 (0.97–1.48)

  HR (95% CI)^b

1.00 (0.99–1.00)

1.00 (reference)

1.07 (0.86–1.34)

1.18 (0.94–1.47)

  HR (95% CI)^c

1.00 (0.99–1.00)

1.00 (reference)

1.13 (0.90–1.42)

1.21 (0.96–1.52)

 Stroke, hemorrhagic

  Number of events

45

44

37

  Person-years

61,492

61,944

62,055

  Event rate per 100,000 py^a

73.2

71.0

9.6

  HR (95% CI)^a

1.00 (0.98–1.00)

1.00 (reference)

0.97 (0.64–1.47)

0.85 (0.55–1.31)

  HR (95% CI)^b

0.99 (0.98–1.00)

1.00 (reference)

0.82 (0.52–1.27)

0.78 (0.49–1.23)

  HR (95% CI)^c

0.99 (0.98–1.00)

1.00 (reference)

0.82 (0.51–1.30)

0.83 (0.51–1.33)

Female

 Stroke, ischemic and hemorrhagic

  Number of events

426

332

293

  Person-years

124,613

126,982

127,036

  Event rate per 100,000 py^a

341.9

261.5

230.6

  HR (95% CI)^a

1.00 (0.99–1.00)

1.00 (reference)

1.00 (0.87–1.16)

0.89 (0.77–1.04)

  HR (95% CI)^b

1.00 (0.99–1.00)

1.00 (reference)

1.00 (0.86–1.18)

0.91 (0.77–1.07)

  HR (95% CI)^c

1.00 (0.99–1.00)

1.00 (reference)

1.07 (0.91–1.26)

0.98 (0.83–1.17)

 Stroke, ischemic

  Number of events

290

203

203

  Person-years

124,612

126,982

127,036

  Event rate per 100,000 py^a

232.7

159.9

159.8

  HR (95% CI)^a

1.00 (0.99–1.00)

1.00 (reference)

0.92 (0.77–1.10)

0.93 (0.77–1.11)

  HR (95% CI)^b

1.00 (0.99–1.00)

1.00 (reference)

0.91 (0.75–1.11)

0.92 (0.76–1.12)

  HR (95% CI)^c

1.00 (0.99–1.00)

1.00 (reference)

0.96 (078–1.17)

1.00 (0.82–1.23)

 Stroke, hemorrhagic

  Number of events

69

70

47

  Person-years

124,613

126,982

127,036

  Event rate per 100,000 py^a

55.4

55.1

37.0

  HR (95% CI)^a

0.99 (0.98–1.00)

1.00 (reference)

1.21 (0.86–1.69)

0.82 (0.56–1.19)

  HR (95% CI)^b

0.99 (0.97–1.00)

1.00 (reference)

1.30 (0.91–1.86)

0.90 (0.61–1.34)

  HR (95% CI)^c

0.99 (0.98–1.00)

1.00 (reference)

1.45 (0.99–2.11)

1.01 (0.67–1.53)