Table 2 Joinpoint trend analysis of liver cancer age-standardized incidence, mortality, and 1-MIR rates worldwide by sex, 1990–2019

Incidence

Trend 1

1990–1994

2.70*(2.30,3.10)

1990–1994

3.20*(2.80,3.60)

1990–1995

1.30*(1.20,1.50)

Trend 2

1994–1998

−0.10(−0.70,0.50)

1994–1998

0.10(−0.60,0.70)

1995–2000

−1.30*(−1.50,-1)

Trend 3

1998–2001

−2.60*(−3.80,-1.40)

1998–2001

−2.50*(−3.80,-1.30)

2000–2005

−6.0*(−6.20,-5.70)

Trend 4

2001–2004

−8.90*(−10,-7.70)

2001–2004

−9.40*(−10.60,-8.30)

2005–2015

− 0.60*(− 0.70,-0.50)

Trend 5

2004–2007

−2.40*(−3.60,-1.20)

2004–2007

−2.60*(−3.80,-1.30)

2015–2019

−0.10(− 0.40,0.10)

Trend 6

2007–2019

0(−0.10,0)

2007–2019

0.10*(0,0.20)

AAPC

1990–2019

−1.10*(−1.40,-0.90)

1990–2019

− 1.10*(− 1.30,-0.80)

1990–2019

− 1.30*(− 1.40,-1.20)

Mortality

Trend 1

1990–1996

1.90*(1.70,2.20)

1990–1996

2.40*(2.10,2.70)

1990–1996

0.90*(0.80,1.10)

Trend 2

1996–2000

−1.70*(− 2.30,-1.10)

1996–2000

− 1.50*(− 2.30,-0.80)

1996–2000

− 2.0*(− 2.40,-1.60)

Trend 3

2000–2004

−8.90*(− 9.50,-8.30)

2000–2004

− 9.40*(− 10.10,-8.80)

2000–2004

−7.20*(−7.60,-6.80)

Trend 4

2004–2012

− 1.20*(− 1.30,-1)

2004–2011

− 1.30*(− 1.60,− 1.10)

2004–2012

-1.10*(− 1.30,-1)

Trend 5

2012–2019

0.20*(0,0.30)

2011–2019

0.20*(0,0.40)

2012–2019

− 0.30*(− 0.40,-0.20)

AAPC

1990–2019

− 1.40*(− 1.50,− 1.30)

1990–2019

-1.30*(− 1.50,-1.20)

1990–2019

−1.50*(− 1.60,-1.40)

1-MIR

Trend 1

1990–1992

34.30*(10.80,62.70)

1990–1992

22.90*(3.60,45.70)

–

–

Trend 2

1992–1999

−7.50*(− 10.40,-4.40)

1992–1999

− 7.0*(− 9.60,-4.30)

–

–

Trend 3

1999–2002

65.50*(36.50,100.50)

1999–2002

54.80*(30.60,83.60)

–

–

Trend 4

2002–2005

−16.60(− 31.10,1.10)

2002–2005

−13.90(− 27.40,2.10)

–

–

Trend 5

2005–2012

5.70*(2.30,9.20)

2005–2012

5.30*(2.30,8.30)

–

–

Trend 6

2012–2019

−0.40(− 2.90,2.20)

2012–2019

− 0.10(− 2.40,2.20)

–

–

AAPC

1990–2019

4.90*(1.70,8.10)

1990–2019

3.90*(1.20,6.80)

–

–