Mean kinetic temperature evaluations through simulated temperature excursions and risk assessment with oral dosage usage for health programs

Table 2 Kinetic parameters incorporated for the different temperature excursion calculations based on a zero-order assumption, 30-day month, and default activation energy (E_a) of 83.144 kJ/mol [2, 4]

Scenario	% Label Claim (LC) - Assay	Days (through shelf life)	k (% LC / day)	A (%LC / day)
1	100	0	0.01389	5.15371 × 10¹²
1	90	720	0.01389	5.15371 × 10¹²
2	100	0	0.00556	2.06148 × 10¹²
2	90	1800	0.00556	2.06148 × 10¹²
3	100	0	0.01389	2.96332 × 10¹²
3	90	720	0.01389	2.96332 × 10¹²
4	100	0	0.00556	1.18533 × 10¹²
4	90	1800	0.00556	1.18533 × 10¹²

ISSN: 1471-2458