The relationship between Social Determinants of Health (SDoH) and death from cardiovascular disease or opioid use in counties across the United States (2009–2018)

Table 5 Impact of significant SDoH predictors on mean opioid use death rate

	Mean	S.D	Coefficient value (estimated effect on opioid use death rate per 100,000)	Percent change in mean of DV based on coefficient value^a	Effect size per 100,000^b	Percent change in mean of DV based on effect size^c
Mean of Dependent Variable (Opioid Use Death Rate) in the sample is 17.82 per 100,000
COUNTY & YEAR EFFECTS
ACS_PCT_FEMALE	50.03082	2.420218	-2.97943	-16.7196%	-7.210870116	-40.46504%
ACS_PCT_PERSON_INC99	16.9234	8.297911	0.9581279	5.3767%	7.950460041	44.61538%
ACS_PCT_VA	10.18986	3.068378	-1.593724	-8.9435%	-4.89014766	-27.44191%
ACS_PCT_MOBILE_HOME	12.78241	9.492498	1.157881	6.4976%	10.99118308	61.67892%
COUNTY, YEAR, & STATE-BY-YEAR FIXED EFFECTS
ACS_MEDIAN_AGE	40.46141	5.203414	-1.818271	-10.2035%	-9.461216777	-53.09325%
ACS_PCT_HISPAN	83.3241	19.15072	-0.7622937	-4.2777%	-14.59847321	-81.92185%
ACS_MEDIAN_HH_INCOME	46,030.93	13,128.92	-0.0002722	-0.0015%	-3.573692024	-20.05439%
ACS_PCT_VA	10.18986	3.068378	-1.352879	-7.5919%	-4.15114416	-23.29486%

^a(Coefficient on SDoH IV divided by mean of DV)*100 provides percent change in mean of DV based on coefficient value
^bCoefficient on SDoH IV multiplied by standard deviation of IV provides effect size of IV per 100,000
^c(Effect size of SDoH IV divided by mean of DV)*100 provides percent change in mean of DV based on effect size