Table 4 Multivariable Cox regression, Model 1 (HT), adjusted for follow-up time. Separate by gender and age groups (age at AF diagnosis). Hazard ratios (95% confidence interval)

Female

Education

Low

1.0 (ref)

1.0 (ref)

1.0 (ref)

1.0 (ref)

1.0 (ref)

Medium

1.31 (1.19 - 1.45)

1.23 (0.95 - 1.60)

1.27 (1.03 - 1.56)

1.28 (1.10 - 1.48)

1.51 (1.17 - 1.94)

High

1.34 (1.19 - 1.51)

1.01 (0.77 - 1.33)

1.26 (1.00 - 1.59)

1.53 (1.28 - 1.83)

1.56 (1.12 - 2.18)

Income

Low

1.0 (ref)

1.0 (ref)

1.0 (ref)

1.0 (ref)

1.0 (ref)

Medium

1.20 (1.10 - 1.31)

1.15 (0.91 - 1.46)

1.33 (1.11 - 1.60)

1.13 (0.99 - 1.29)

1.20 (0.95 - 1.51)

High

1.40 (1.23 - 1.59)

1.52 (1.14 - 2.03)

1.42 (1.10 - 1.82)

1.34 (1.10 - 1.64)

1.54 (0.96 - 2.46)

Hospital referral area (HT)

Finnmark (N)

0.39 (0.23 - 0.66)

0.44 (0.14 - 1.40)

0.54 (0.22 - 1.32)

0.29 (0.12 - 0.71)

0.43 (0.10 - 1.80)

UNN (N)

0.52 (0.39 - 0.69)

0.72 (0.39 - 1.34)

0.62 (0.35 - 1.10)

0.42 (0.27 - 0.66)

0.52 (0.23 - 1.16)

Nordland (N)

0.45 (0.32 - 0.63)

0.33 (0.10 - 1.05)

0.52 (0.26 - 1.04)

0.44 (0.27 - 0.72)

0.53 (0.23 - 1.25)

Helgeland (N)

0.73 (0.53 - 1.00)

0.29 (0.13 - 0.67)

0.68 (0.34 - 1.35)

1.08 (0.70 - 1.66)

0.90 (0.38 - 2.12)

Nord-Trøndelag (C)

0.86 (0.66 - 1.12)

0.67 (0.32 - 1.40)

0.99 (0.58 - 1.70)

0.90 (0.62 - 1.29)

0.65 (0.28 - 1.54)

St. Olavs (C)

1.50 (1.26 - 1.78)

0.92 (0.56 - 1.51)

1.32 (0.91 - 1.91)

1.61 (1.25 - 2.06)

2.23 (1.45 - 3.43)

Møre-Romsdal (C)

1.19 (0.99 - 1.44)

1.06 (0.63 - 1.77)

1.02 (0.69 - 1.52)

1.32 (1.01 - 1.73)

1.34 (0.79 - 2.26)

Førde (W)

0.81 (0.60 - 1.10)

0.41 (0.15 - 1.12)

0.82 (0.43 - 1.54)

0.94 (0.62 - 1.43)

0.84 (0.38 - 1.87)

Bergen (W)

1.09 (0.92 - 1.29)

0.82 (0.52 - 1.27)

1.18 (0.83 - 1.67)

1.00 (0.78 - 1.29)

1.57 (1.02 - 2.41)

Fonna (W)

1.18 (0.96 - 1.47)

0.78 (0.44 - 1.36)

1.18 (0.74 - 1.88)

1.30 (0.96 - 1.76)

1.38 (0.79 - 2.44)

Stavanger (W)

0.38 (0.32 - 0.46)

0.20 (0.14 - 0.29)

0.43 (0.30 - 0.63)

0.59 (0.44 - 0.78)

0.71 (0.41 - 1.22)

Østfold (SE)

0.84 (0.69 - 1.02)

0.71 (0.43 - 1.17)

0.92 (0.62 - 1.38)

0.90 (0.68 - 1.19)

0.65 (0.36 - 1.18)

Akershus (SE)

0.81 (0.69 - 0.96)

0.91 (0.62 - 1.33)

0.85 (0.61 - 1.19)

0.76 (0.60 - 0.97)

0.80 (0.50 - 1.27)

OUS (SE)

0.90 (0.73 - 1.10)

0.82 (0.52 - 1.31)

1.21 (0.82 - 1.79)

0.77 (0.56 - 1.06)

0.89 (0.50 - 1.59)

Lovisenberg (SE)

0.97 (0.71 - 1.32)

1.16 (0.65 - 2.08)

0.54 (0.23 - 1.23)

1.09 (0.70 - 1.69)

0.56 (0.13 - 2.30)

Diakonhjemmet (SE)

0.91 (0.70 - 1.17)

1.09 (0.60 - 1.99)

0.82 (0.46 - 1.45)

0.70 (0.46 - 1.06)

1.58 (0.88 - 2.82)

Innlandet (SE)

0.67 (0.56 - 0.81)

0.79 (0.52 - 1.21)

0.98 (0.69 - 1.37)

0.48 (0.36 - 0.65)

0.74 (0.44 - 1.22)

Vestre Viken (SE)

1.0 (ref)

1.0 (ref)

1.0 (ref)

1.0 (ref)

1.0 (ref)

Vestfold (SE)

0.78 (0.64 - 0.95)

0.55 (0.33 - 0.93)

0.96 (0.66 - 1.40)

0.76 (0.56 - 1.02)

0.88 (0.51 - 1.52)

Telemark (SE)

1.05 (0.86 - 1.29)

1.23 (0.78 - 1.93)

1.12 (0.74 - 1.69)

0.99 (0.73 - 1.36)

0.81 (0.44 - 1.52)

Sørlandet (SE)

0.90 (0.74 - 1.08)

0.92 (0.61 - 1.41)

1.23 (0.86 - 1.77)

0.78 (0.58 - 1.04)

0.74 (0.43 - 1.29)

Male

Education

Low

1.0 (ref)

1.0 (ref)

1.0 (ref)

1.0 (ref)

1.0 (ref)

Medium

1.28 (1.20 - 1.37)

1.34 (1.15 - 1.56)

1.25 (1.11 - 1.40)

1.30 (1.17 - 1.45)

1.22 (0.99 - 1.52)

High

1.62 (1.51 - 1.74)

1.40 (1.19 - 1.65)

1.48 (1.30 - 1.68)

1.78 (1.58 - 2.00)

2.12 (1.68 - 2.68)

Income

Low

1.0 (ref)

1.0 (ref)

1.0 (ref)

1.0 (ref)

1.0 (ref)

Medium

1.54 (1.42 - 1.67)

1.58 (1.30 - 1.92)

1.72 (1.48 - 2.01)

1.38 (1.23 - 1.56)

1.48 (1.18 - 1.85)

High

1.84 (1.69 - 2.00)

1.69 (1.39 - 2.06)

2.07 (1.77 - 2.41)

1.69 (1.49 - 1.91)

1.86 (1.42 - 2.43)

Hospital referral area (HT)

Finnmark (N)

0.62 (0.48 - 0.80)

0.86 (0.49 - 1.52)

0.49 (0.31 - 0.78)

0.60 (0.41 - 0.88)

0.88 (0.42 - 1.81)

UNN (N)

0.81 (0.70 - 0.94)

1.12 (0.81 - 1.53)

0.92 (0.73 - 1.17)

0.66 (0.51 - 0.84)

0.55 (0.32 - 0.94)

Nordland (N)

0.82 (0.70 - 0.97)

1.01 (0.69 - 1.47)

0.89 (0.68 - 1.18)

0.73 (0.57 - 0.95)

0.62 (0.34 - 1.11)

Helgeland (N)

0.80 (0.66 - 0.97)

0.61 (0.36 - 1.04)

0.88 (0.63 - 1.22)

0.81 (0.59 - 1.10)

0.80 (0.41 - 1.54)

Nord-Trøndelag (C)

1.14 (0.98 - 1.32)

1.45 (1.04 - 2.01)

1.23 (0.94 - 1.62)

0.94 (0.74 - 1.20)

1.09 (0.67 - 1.79)

St. Olavs (C)

1.78 (1.61 - 1.97)

1.87 (1.47 - 2.39)

1.75 (1.46 - 2.09)

1.70 (1.45 - 1.99)

1.99 (1.46 - 2.70)

Møre-Romsdal (C)

1.24 (1.10 - 1.39)

1.46 (1.10 - 1.93)

1.30 (1.06 - 1.60)

1.13 (0.94 - 1.35)

1.10 (0.75 - 1.62)

Førde (W)

0.83 (0.70 - 1.00)

1.16 (0.77 - 1.74)

0.72 (0.52 - 1.01)

0.81 (0.61 - 1.07)

0.80 (0.46 - 1.38)

Bergen (W)

1.27 (1.15 - 1.40)

1.25 (0.98 - 1.59)

1.21 (1.01 - 1.44)

1.30 (1.12 - 1.52)

1.32 (0.97 - 1.80)

Fonna (W)

1.29 (1.13 - 1.46)

1.38 (1.01 - 1.89)

1.15 (0.91 - 1.46)

1.31 (1.08 - 1.59)

1.39 (0.93 - 2.07)

Stavanger (W)

0.65 (0.58 - 0.72)

0.61 (0.48 - 0.77)

0.60 (0.49 - 0.73)

0.75 (0.63 - 0.90)

0.74 (0.50 - 1.09)

Østfold (SE)

0.95 (0.85 - 1.07)

1.09 (0.83 - 1.44)

0.98 (0.80 - 1.21)

0.83 (0.69 - 1.01)

1.07 (0.74 - 1.54)

Akershus (SE)

0.94 (0.85 - 1.04)

1.13 (0.90 - 1.44)

1.00 (0.84 - 1.20)

0.82 (0.69 - 0.97)

0.87 (0.63 - 1.21)

OUS (SE)

1.00 (0.89 - 1.13)

1.39 (1.08 - 1.80)

1.03 (0.83 - 1.27)

0.86 (0.71 - 1.05)

0.87 (0.58 - 1.31)

Lovisenberg (SE)

0.90 (0.73 - 1.10)

0.83 (0.55 - 1.24)

1.00 (0.70 - 1.44)

1.05 (0.76 - 1.46)

0.49 (0.18 - 1.33)

Diakonhjemmet (SE)

1.02 (0.88 - 1.18)

1.08 (0.76 - 1.53)

1.07 (0.80 - 1.42)

0.95 (0.76 - 1.18)

1.05 (0.68 - 1.62)

Innlandet (SE)

0.80 (0.71 - 0.89)

0.94 (0.72 - 1.23)

0.85 (0.70 - 1.04)

0.74 (0.62 - 0.88)

0.62 (0.42 - 0.90)

Vestre Viken (SE)

1.0 (ref)

1.0 (ref)

1.0 (ref)

1.0 (ref)

1.0 (ref)

Vestfold (SE)

0.87 (0.77 - 0.99)

0.96 (0.71 - 1.30)

1.05 (0.86 - 1.29)

0.75 (0.62 - 0.92)

0.61 (0.39 - 0.94)

Telemark (SE)

1.13 (1.00 - 1.28)

1.27 (0.95 - 1.69)

1.21 (0.97 - 1.51)

1.11 (0.91 - 1.35)

0.73 (0.45 - 1.16)

Sørlandet (SE)

0.98 (0.87 - 1.10)

1.22 (0.93 - 1.59)

1.08 (0.88 - 1.32)

0.85 (0.70 - 1.02)

0.80 (0.54 - 1.18)