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Table 4 Association between daytime napping and fasting plasma glucose with mediation by body mass index, waist circumference, hip circumference, waist-to-hip ratio, and waist-to-height ratio in 27,018 participants without type 2 diabetes history in the Guangzhou Biobank Cohort Study

From: Obesity indicators as mediators of association between daytime napping and type 2 diabetes mellitus: the Guangzhou Biobank Cohort Study

Mediatorsa

Indirect effect (ACME) Estimate (95% CI)b

Direct effect (ADE) Estimate (95% CI)b

Total effect Estimate (95% CI)b

Proportion via mediation % (95% CI)b

Body mass index, kg/m2

−0.0002 (− 0.0046, 0.0039)

0.0732 (0.0431, 0.1039)*

0.0731 (0.0418, 0.1049)*

−0.24 (− 0.41, − 0.16)

Waist circumference, cm

0.0106 (0.0051, 0.0158)*

0.0625 (0.0324, 0.0930)*

0.0731 (0.0417, 0.1049)*

14.57 (10.11, 25.40)*

Hip circumference, cm

0.0016 (−0.0016, 0.0046)

0.0716 (0.0413, 0.1023)*

0.0731 (0.0420, 0.1048)*

2.13 (1.48, 3.70)

Waist-to-hip ratio

0.0133 (0.0081, 0.0182)*

0.0598 (0.0297, 0.0904)*

0.0731 (0.0417, 0.1050)*

18.22 (12.63, 31.78)*

Waist-to-height ratio

0.0095 (0.0042, 0.0146)*

0.0635 (0.0335, 0.0940)*

0.0731 (0.0417, 0.1049)*

13.12 (9.10, 22.89)*

  1. Abbreviations: ACME average causal mediated effect, ADE average direct effect
  2. aAll mediators were standardized using Z-scores to facilitate comparison
  3. bAdjusting for sex, age, education, occupation, smoking status, alcohol use, and physical activity
  4. *P < 0.05