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Table 3 Hazard ratios (HRs) and 95% confidence intervals (CI) for transition from MHO to MUO phenotype based on tertiles of wrist circumference in males

From: Wrist circumference as a novel predictor of transition from metabolically healthy to unhealthy phenotype in overweight/obese adults: a gender-stratified 15.5-year follow-up

 

Unadjusted

Age-adjusted

Model 1

Model 2

 

HR (%95 CI)

P -value

HR (%95 CI)

P -value

HR (%95 CI)

P -value

HR (%95 CI)

P -value

Wrist circumference

 Tertile 1 (<17.5 cm)

1.00 (reference)

 

1.00 (reference)

 

1.00 (reference)

 

1.00 (reference)

 

 Tertile 2 (17.5-18.0 cm)

0.89 (0.64-1.24)

0.489

0.86 (0.62-1.20)

0.377

0.89 (0.63-1.27)

0.522

0.92 (0.64-1.32)

0.661

 Tertile 3 (>18.0 cm)

1.31 (0.99-1.73)

0.060

1.16 (0.87-1.55)

0.314

1.15 (0.84-1.59)

0.372

1.18 (0.83-1.67)

0.352

P for trend

0.027

0.165

0.306

0.352

Age

  

1.26 (1.12-1.39)

0.001

1.24 (1.07-1.43)

0.004

1.28 (1.08-1.50)

0.004

Smoking

    

1.07 (0.79-1.45)

0.667

1.08 (0.79-1.46)

0.634

Education level (below diploma)

    

1.18 (0.86-1.61)

0.308

1.18 (0.86-1.61)

0.313

Low physical activity

    

1.16 (0.88-1.54)

0.293

1.13 (0.85-1.50)

0.395

SBP

    

0.97 (0.82-1.14)

0.714

0.98 (0.83-1.16)

0.799

DBP

    

1.09 (0.93-1.29)

0.294

1.08 (0.92-1.28)

0.343

FPG

    

1.22 (1.02-1.46)

0.028

1.24 (1.03-1.48)

0.019

2-h PG

    

1.03 (0.90-1.18)

0.670

1.01 (0.88-1.16)

0.832

Triglycerides

    

1.09 (0.97-1.23)

0.153

1.10 (0.97-1.24)

0.124

HDL

    

0.75 (0.63-0.90)

0.001

0.73 (0.61-0.88)

0.001

Body mass index

       

1.36 (1.07-1.73)

0.013

Waist circumference

       

0.85 (0.66-1.08)

0.179

Hip circumference

       

0.91 (0.68-1.21)

0.510

  1. Hazard ratios for the continuous variables are reported per 1 standard deviation
  2. SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, 2-h PG 2-h post-challenge plasma glucose, HDL high-density lipoprotein, LDL low-density lipoprotein