LTBI screening threshold | Total costs* (million €) | TB cases prevented | QALYs gained | Incr. costs* (million €) | Incr. TB cases prevented | Incr. QALYs gained | ICER (Thsd. € per TB case prevented) | ICER (Thsd. € per QALY gained |
---|---|---|---|---|---|---|---|---|
≥ 250 | 0.31 (0.20–0.42) | 16 (7–32) | 7.3 (2.7–14.8) | 0.31 (0.20–0.42) | 16 (7–32) | 7.3 (2.7–14.8) | 22.3 (8.2–50.0) | 51.0 (18.0–114.1) |
≥ 200 | 0.56 (0.38–0.77) | 29 (12–56) | 13.2 (4.9–26.3) | 0.25 (0.17–0.35) | 13 (5–25) | 5.8 (2.1–11.6) | 23.3 (8.6–52.2) | 53.3 (19.1–122.5) |
≥ 150 | 1.10 (0.74–1.52) | 56 (23–105) | 24.9 (9.3–49.9) | 0.54 (0.37–0.74) | 26 (11–50) | 11.8 (4.4–23.7) | 24.5 (9.2–53.7) | 55.9 (20.2–128.2) |
≥ 100 | 1.19 (0.80–1.63) | 60 (24–113) | 26.6 (9.9–53.5) | 0.09 (0.06–0.12) | 4 (2–7) | 1.7 (0.6–3.3) | 27.1 (10.5–59.8) | 62.0 (23.2–142.0) |
≥ 50 | 1.66 (1.13–2.27) | 75 (31–142) | 33.6 (12.5–67.1) | 0.47 (0.33–0.66) | 16 (6–30) | 6.9 (2.6–13.8) | 36.0 (14.7–78.4) | 82.4 (31.6–184.7) |
≥ 20 | 2.04 (1.39–2.78) | 84 (34–157) | 37.7 (14.0–74.7) | 0.38 (0.26–0.54) | 9 (4–18) | 4.1 (1.5–8.7) | 48.7 (19.8–106.7) | 111.8 (42.7–251.9) |
None† | 2.91 (2.02–4.02) | 100 (41–187) | 44.8 (16.8–88.3) | 0.87 (0.60–1.25) | 16 (5–35) | 7.1 (2.2–16.3) | 68.0 (26.1–158.7) | 156.3 (54.4–373.3) |