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Table 3 Recent substance use and condomless sex

From: Individual and poly-substance use and condomless sex among HIV-uninfected adults reporting heterosexual sex in a multi-site cohort

Recent substance use

RR

95% CI

p-value

Overall

 Nonea

Ref

–

–

 Single substance

1.08

1.05–1.11

< 0.001

 Polysubstance

1.09

1.05–1.13

< 0.001

 Single- vs. poly-substance

1.02

0.99–1.05

0.26

Overall – Illicit substance use only

 Noneb

Ref

–

–

 Single substance

1.06

1.02–1.09

0.002

 Polysubstance

1.09

1.05–1.13

< 0.001

 Single- vs. poly-substance

1.01

0.97–1.05

0.68

By type of sex

 Vaginal sex only

Ref

–

–

 Vaginal and anal sex

1.21

1.16–1.26

< 0.001

Vaginal sex only

 Nonea

Ref

–

–

 Single substance

1.09

1.05–1.14

< 0.001

 Polysubstance

1.10

1.05–1.15

< 0.001

 Single- vs. poly-substance

1.01

0.96–1.05

0.81

Vaginal and anal sex

 Nonea

Ref

–

–

 Single substance

1.05

1.02–1.09

0.004

 Polysubstance

1.08

1.04–1.12

< 0.001

 Single- vs. poly-substance

1.03

0.99–1.06

0.12

By HIV status of partner

 HIV-negative partners only

Ref

–

–

 HIV-unknown partners only

0.92

0.86–0.98

0.01

 HIV-negative & HIV-unknown partners only

1.11

1.04–1.19

0.001

HIV-negative partners only

 Nonea

Ref

  

 Single substance

1.08

1.02–1.13

0.004

 Polysubstance

1.07

1.01–1.14

0.02

 Single- vs. poly-substance

0.99

0.94–1.05

0.81

HIV-unknown partners only

 Nonea

Ref

–

–

 Single substance

1.04

0.95–1.13

0.39

 Polysubstance

0.97

0.88–1.07

0.57

 Single- vs. poly-substance

0.94

0.85–1.03

0.20

HIV-negative & HIV-unknown partners only

 Nonea

Ref

–

–

 Single substance

1.09

1.01–1.18

0.03

 Polysubstance

1.13

1.06–1.20

< 0.001

 Single- vs. poly-substance

1.04

0.98–1.10

0.22

  1. Abbreviations: CI Confidence interval, RR Relative risk
  2. Models adjusted for age, race/ethnicity, and gender
  3. a None included participants who reported no binge alcohol use or illicit drug use (non-binge alcohol use and cannabis use allowed)
  4. b None included participants who reported no illicit drug use (any alcohol use and cannabis use allowed)