Model 1 | Model 2 | |||
---|---|---|---|---|
Variables | Odds ratio (95% CI) | p-value | Odds ratio (95% CI) | p-value |
HbA1c status | ||||
Group A | Ref. | Ref. | ||
Group B | 22.64 (14.66–34.99) | < 0.001 | 3.02 (0.84–10.97) | 0.09 |
Group C | 90.83 (76.33–108.08) | < 0.001 | 0.54 (0.25–1.18) | 0.12 |
Group D | 36.95 (33.10–41.26) | < 0.001 | 0.28 (0.12–0.61) | < 0.01 |
Number of health check-ups between April 2014 and March 2018 | ||||
0 | Ref. | Ref. | ||
1 | 0.84 (0.66–1.08) | 0.19 | 0.52 (0.20–1.38) | 0.19 |
2 | 0.99 (0.79–1.25) | 0.94 | 0.45 (0.18–1.14) | 0.09 |
3 | 1.04 (0.84–1.29) | 0.73 | 0.24 (0.09–0.61) | < 0.01 |
4 | 0.88 (0.72–1.07) | 0.20 | 0.19 (0.09–0.42) | < 0.001 |
Age, years | 1.01 (1.00–1.01) | 0.08 | 0.98 (0.95–1.01) | 0.17 |
Sex | ||||
Female | 1.05 (0.92–1.20) | 0.48 | 1.13 (0.63–2.05) | 0.68 |
Male | Ref. | Ref. | ||
BMI | 1.08 (1.07–1.10) | < 0.001 | – | |
SBP, mmHg | 1.01 (1.00–1.01) | < 0.001 | – | |
DBP, mmHg | 0.99 (0.98–0.99) | < 0.001 | – | |
Triglyceride, mg/dL | 1.00 (1.00–1.00) | < 0.01 | ||
HDL, mg/dL | 0.99 (0.99–0.99) | < 0.001 | 1.02 (1.00–1.03) | 0.06 |
GOT, IU/L | 0.99 (0.99–1.00) | 0.06 | – | |
GPT, IU/L | 1.01 (1.01–1.02) | < 0.001 | – | |
γ-GTP, IU/L | 1.00 (1.00–1.00) | < 0.001 | – | |
Hemoglobin, g/dL | 1.10 (1.05–1.14) | < 0.001 | – | |
Uric acid, mg/dL | – | – | ||
Serum creatinine, mg/dL | 1.31 (0.99–1.71) | 0.06 | – | |
eGFR, mL/min | 1.01 (1.00–1.01) | < 0.001 | ||
Urine glucose | ||||
Negative | Ref. | Ref. | ||
Trace | 1.19 (0.84–1.69) | 0.33 | 3.18 (1.01–10.00) | < 0.05 |
1+ | 1.69 (1.20–2.37) | < 0.01 | 1.27 (0.29–5.64) | 0.75 |
2+ | 2.47 (1.55–3.92) | < 0.001 | 4.72 (1.45–15.36) | < 0.05 |
3+ | 2.39 (1.58–3.63) | < 0.001 | 2.65 (0.83–8.44) | 0.10 |
Urine protein (n, %) | ||||
Negative | Ref. | Ref. | ||
Trace | 1.14 (0.97–1.33) | 0.10 | 1.39 (0.60–3.22) | 0.44 |
1+ | 1.27 (1.02–1.57) | < 0.05 | 2.24 (0.92–5.47) | 0.08 |
2+ | 1.21 (0.82–1.80) | 0.34 | 1.89 (0.42–8.49) | 0.41 |
3+ | 1.59 (0.85–2.98) | 0.15 | – | |
Anti-hypertensive drugs | 1.32 (1.19–1.47) | < 0.001 | – | |
Lipid-lowering drugs | 1.37 (1.24–1.52) | < 0.001 | 0.37 (0.17–0.78) | < 0.01 |
Treatment history | ||||
Cerebrovascular disease | 1.19 (0.97–1.46) | 0.09 | – | |
Daily smoking | 1.14 (0.98–1.33) | 0.08 | – |