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Table 2 General characteristics of included RCTs (n = 18)

From: Determining what constitutes an effective psychosocial ‘return to work’ intervention: a systematic review and narrative synthesis

Study

Country

n

Target Population

Intervention 1

Intervention 2

RTW Measure(s)

Secondary Outcome(s)

Description

Provider(s)

Description

Provider

Aasdahl, Pape [25]

Norway

168

Adults with musculoskeletal or mental health disorders, on 50–100% sick leave for 2–12 months

Outpatient group-based ACT in addition to 2 individual sessions to clarify personal values and work-related issues; homework assigned between sessions including daily 15-min mindfulness practice; group-based motivational discussion about benefits of physical training; concluding with an individual session to write a letter to GP

Physician, psychologist, social worker, physiotherapist

Inpatient multi-component intervention including group ACT, physical training, mindfulness, psychoeducation, problem solving, RTW plan creation

Mentors / coordinators, rehabilitation center staff

Number of sickness absence days and time until RTW (1 month without relapse)

None

Andersen, Birgit [26]

Denmark

141

Adults with pain in back or upper body, mixed employment status, on sick leave for a maximum of 9-weeks

Health guidance dialogue about lifestyle, motivation, resources, power to act; opportunity to create health plan for improving daily wellbeing

Health supervisor

Health guidance + tailored physical activity: group fitness and strength training

OR

Health supervisor, physiotherapists

RTW status

Pain; BMI; aerobic capacity; work ability; kinesiophobia

Health guidance + chronic pain self-management including group-based problem solving, exercise, and psychoeducation

Health supervisor, trained non-health professional facilitators

Bitsch, Nielsen [27]

Denmark

244

Adults with ischemic heart disease or heart failure undergoing cardiac rehabilitation

Standard cardiac rehabilitation involving structured deductive teaching (pre-written slideshows) without rationale; education topics included lifestyle implications, emotional reactions, importance of social networks, importance of exercise, future life with chronic disease

Nurse, physiotherapist, experienced patients

Learning and coping (LC) education program in addition to standard cardiac rehabilitation; inductive learning with rationale; 2 individual clarifying interviews

Nurse, physiotherapist, experienced patients, LC trained health professionals

RTW status and relapse (RTW, but not at work 1 year later)

None

Brendbekken, Eriksen [28]

Norway

284

Adults with musculoskeletal pain, on 50–100% sick leave for less than 12 months

Brief intervention focusing on education, reduction of fear and concern, helping patient stay active; opportunity for patient to express problems and worries; thorough medical and educational examination

Physician, physiotherapist

Multi-disciplinary comprehensive intervention involving multiple interviews and assessments, visual feedback tools

Social worker, physician, physiotherapist

Full-time RTW status

None

De Weerd, Van Dijk [29]

Netherlands

60

Adults with common psychological disorders, employed and on part-time sick leave

Work-focused CBT focusing on activation, day structure, socialising, and self-worth within a work context

Provisional and registered psychologists

Work-focused CBT plus a 1.5 h convergence dialogue meeting between patient, employer, and psychologist discussing RTW

Provisional and registered psychologists, supervisor

Time until first and full RTW

Mental health

Du Bois and Donceel [30]

Belgium

506

Adults with low back pain, employed and on sick leave

Rehabilitation-oriented coaching involving medical and psychosocial education, importance of activity, response rates, and encouragement based on resilience

Physician

CAU involving brief disability evaluation without medical advice

Unclear

RTW status; sick leave recurrence; sick leave duration

Subsequent surgery

Finnes, Ghaderi [31]

Sweden

352

Adults with common psychological disorders, employed and on 25–100% sick leave for previous 1–12 months

ACT alone involving some work focus, psychoeducation about avoidance patterns, mindfulness, diffusion, self-compassion, value-driven behaviour, exposure exercises

Psychologists

WDI: three-steps, to facilitate dialogue between participant and workplace

OR

WDI + ACT

OR

TAU: saw medical doctors, psychologists, social workers, physical therapists, and nurses in the study period.

Supervisor, psychologists, medical doctors, social workers, physical therapists, and nurses

Number of sickness absence days

Work ability; general functioning; exhaustion; depression; anxiety

Glasscock, Carstensen [32]

Denmark

137

Adults with work-related adjustment, stress or mild depression, employed and on sick leave for < 4 months

Individual work-focused CBT; psycho-education; establishing shared treatment goals; stress coping; cognitive restructuring; relapse prevention; workplace intervention involving meeting with employers with option of psychologist attendance

Psychologists

No-treatment control group

N/A

Lasting RTW (> 4 weeks)

Stress; general health

Lytsy, Carlsson [33]

Sweden

308

Adult females with pain or mental illness, mixed employment status and about to reach maximum sick leave duration of 1 year

ACT focused on behavioural strategies to increase function and quality of life, rather than symptom reduction

Psychologists

Multidisciplinary assessments, creation of individualised rehabilitation plans, and weekly meetings to evaluate / synchronise plans and activities. ACT was an option where suggested by the team.

OR

“Usual care” by regular health contacts

Physician, psychologist, occupational therapist, social worker.

Insurance status; insurance days; working hours; work engagement

None

Myhre, Marchand [34]

Norway

405

Adults with neck and back pain, employed and on sick leave for 1–12 months

Pain-related coaching: standard clinical examination; education about importance of activity; focus on reduction in fear-avoidance beliefs; self-care and coping

Physician, physiotherapist

Pain-related coaching plus appointments with caseworker focusing on RTW, opportunity for a meeting with employer

Physician, caseworker, physiotherapist

Lasting absence (5 weeks) of welfare benefits

None

Nieuwenhuijsen, Antonius [35]

Netherlands

96

Adults with work-related chronic stress (neurasthenia), employed and on part- or full-time sick leave

RTW and mental health coaching focused on reducing burnout and improving wellbeing; problem-solving related to mental health; psycho-education; cognitive restructuring; acceptance and relaxation; employability; conflict and time management; fatigue and stress

Certified coach

RTW and mental health coaching plus light / electromagnetic field therapy

OR

RTW and mental health coaching plus placebo light / electromagnetic therapy

Certified coach

Percentage RTW

Emotional exhaustion; fatigue; quality of life; stress; cortisol

Park, Esmail [36]

Canada

728

Adults with work-related musculoskeletal injuries, mixed employment status

Motivational interviewing focused on enhancing motivation, reducing ambivalence, eliciting reasons for change, discussing ability to change

Case managers, physicians, psychologist, occupational therapists, exercise therapists

CAU involving functional restoration – an interdisciplinary approach that focuses on improving physical and functional abilities, RTW planning, and individual counselling and educational workshops

Various stakeholders, occupational therapists, exercise therapists

RTW status

None

Rolving, Nielsen [37]

Denmark

90

Adults with degenerative disc disease or spondylolisthesis receiving lumbar spinal fusion surgery, mixed employment status

Group-based and standardised preoperative CBT focusing on the relationship between thoughts and pain, cognitive restructuring, coping, pacing, RTW, ergonomics, surgery information, pleasant activity scheduling, problem-solving

Psychologist, occupational therapist, physiotherapist, social worker, spine surgeon, previous patient

CAU involving standard preoperative surgery-related information and postoperative physical rehabilitation

Operating surgeons, nurses, physiotherapists, occupational therapists

RTW status

Disability; fear avoidance; catastrophizing; pain

Salomonsson, Santoft [38]

Sweden

211

Adults with common psychological disorders, on 50–100% sick leave for 1–6 months

Psychological disorder-focused treatment. CBT involving a protocol for the primary diagnosis (e.g., behavioural activation for depression, cognitive therapy for social phobia, exposure for obsessive-compulsive disorder)

Psychologists

RTW-focused CBT only

OR

Psychological disorder and RTW-focused CBT combined

Psychologists

Number of sick leave days

Psychological symptoms; work ability; quality of life; stress

Salzwedel, Wegscheider [39]

Germany

354

Adults with recent acute cardiac event and negative RTW expectations, mixed employment status, unemployed for less than 1 year

Group-based social counselling and therapy focused on legal rights, occupational capacity and health behaviour, promoting social competency such as networking

Social workers

CAU involving cardiac rehabilitation and as-needed counselling

Social workers

RTW status

Quality of life

Vlasveld, van der Feltz-Cornelis [40]

Netherlands

126

Adults with major depressive disorder, on sick leave for 1–3 months

Collaborative care involving structured problem-solving; self-help focused on cognitive restructuring, RTW, and healthy lifestyle; workplace intervention; possible prescription of anti-depressants

Occupational physician, psychiatrist

CAU involving contact with a range of health professionals and treatment for mental health problems in some cases

Occupational physician, GP, mental health professionals, social worker, medical specialist, paramedic, alternative healthcare, self-help group

Time until full RTW

Depression

Volker, Zijlstra-Vlasveld [41]

Netherlands

220

Adults with common psychological disorder, on sick leave for 1–6 months

Web-based blended individually tailored eHealth including several of the following modules: 1) psycho-education, 2) CBT for RTW-related symptoms, 3) problem-solving, 4) pain and fatigue management and reactivation, 5) relapse prevention; consultations with occupational physician

Occupational physician

CAU involving access to various health professionals; regular consultations with occupational physician

Occupational physicians, general practitioner, mental health professional, social worker, self-help group

Time until first RTW; time until full RTW; number of sick leave days

Psychological symptoms

Vonk Noordegraaf, Anema [42]

Netherlands

215

Adult females with hysterectomy and/or laparoscopic adnexal surgery, employed and on sick leave for less than 2 months

Web-based tailored eHealth including pre/post-operative instructions on RTW and daily activities; self-empowerment; communication with stakeholders; identification of recovery barriers; general information on the surgery; frequently asked questions; forum to communicate with other participants

None

Web-based control with generic information related to the surgery

Usual care given by gynaecologists, occupational physicians, and general practitioners

Time until full RTW

Quality of life; general recovery; pain

  1. Note: n number of participants, RTW return to work, ACT Acceptance and Commitment Therapy, CBT Cognitive Behavioural Therapy, GP general practitioner, CAU care as usual, WDI workplace dialogue intervention, GP general practitioner; aWith pre-planned adjusted analyses