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Table 1 Characteristics of selected study articles

From: High prevalence of vitamin D deficiency among the South Asian adults: a systematic review and meta-analysis

Authors

Year

Country

Study area (urban or rural)

Study design

Age

Gender

Socio economic status

Vitamin D estimation method

Sample size (N)

Average level of vitamin D

(ng /mL)

Standard deviation (S.D)

Arya et al. [32]

2003

India

Urban

Hospital – CS

24–53 y

Both

NM

RIA

92

12.3

10.9

Malhotra et al. [33]

2009

India

NM

Hospital – RCT

18 y or above

Female

NM

RIA

100

4.7

3.4

Harinarayan et al. [34]

2011

India

Urban

Hospital – CS

Mean age 38 y

Female

NM

RIA

55

15.7

10.23

Agrawal et al. [35]

2013

India

NM

Hospital – CS

50 y or above

Male

NM

RIA

200

18.96

10.23

Vupputuri et al. [36]

2006

India

Urban

Community – CS

Mean age 43.3 y

Both

Middle

RIA

105

9.8

6

Suryanarayanaet al [37]

2018

India

Urban

Community – CS

60 y or above

Both

Both

RIA

298

19.3

9.32

Shivane et al. [38]

2011

India

Urban

Community – CS

25–35 y

Both

NM

RIA

1137

17.4

9.1

Harinarayan et al. [39]

2006

India

Both

Community – CS

Mean age 44.5 y

Both

Both

RIA

1146

21.135

0.8

Shukla et al. [40]

2016

India

NM

Hospital – CS

More than 20 y

Both

NM

ECLIA

26,273

21.44

14.06

Sanket et al. [41]

2016

India

NM

Hospital – CC

18–65 y

Both

NM

CLIA

81

26.25

NM

Karoli et al. [42]

2014

India

Both

Hospital – CS

18–60 y

Both

Lower

ECLIA

100

30.6

10.8

Laway et al. [43]

2014

India

NM

Hospital – CC

More than 25 y

Both

NM

RIA

102

28.46

18.89

Gupta et al. [44]

2014

India

NM

Hospital – CC

35 y or more

Both

NM

CLIA

70

26.32

14.12

Bhatt et al. [45]

2014

India

Urban

Community – CS

18–60 y

Both

Both

RIA

137

18.9

6.7

Marwaha et al. [46]

2011

India

Urban

Community – CS

More than 50 y

Both

NM

RIA

1346

9.85

7.73

Goswami et al. [47]

2009

India

NM

Community – CS

15–60 y

Both

NM

RIA

642

7

4.08

Zargar et al. [48]

2007

India

Both

Community – CS

18–40 y

Both

NM

RIA

92

10.286

8.215

Harinarayan et al. [49]

2004

India

Both

Community – CS

Mean age 45 y

Both

NM

RIA

316

16.76

5.61

Sofi et al. [50]

2017

India

Both

Hospital – CS

20–49 y

Female

Both

CLIA

224

10.55

7.65

Beloyartseva et al. [51]

2012

India

Urban

Community – CS

Mean age 42.7y

Both

NM

RIA

2119

14.35

10.62

Singh et al. [52]

2018

India

Both

Hospital – CS

20–50 y

Female

NM

CLIA

72

22.91

16.18

Shetty et al. [53]

2014

India

Urban

Community – CS

50 y or above

Male

NM

CLIA

252

20.4

8.3

Kajale et al. [54]

2015

India

Urban

Hospital – CS

Mean age 27.7 y

Female

Both

ELISA

300

15.76

8.8

Goswami et al. [55]

2008

India

Rural

Community – CS

Mean age 42.8 y

Both

NM

RIA

57

14.56

9

Kiran et al. [56]

2014

India

Rural

Community – CS

20–72 y

Both

Both

CMIA

81

15.49

7.58

Kumar et al. [57]

2017

India

NM

Hospital – CC

Mean age 48.2y

Both

NM

CLIA

150

30.6

10.2

Goswami et al. [58]

2016

India

Urban

Community – CS

Mean age 25–32 y

Male

NM

CLIA

194

19.66

6.17

Meena et al. [59]

2016

India

Urban

Hospital – CS

NM

Female

Lower

RIA

100

6.3

4.6

Singh et al. [60]

2011

India

NM

Hospital – CS

Mean age 28 y

Male

NM

RIA

80

9.1

6.54

Garg et al. [61]

2013

India

Urban

Community - CS

50 y or above

Both

NM

RIA

1346

9.8

7.6

Harinarayan et al. [62]

2011

India

Urban

Hospital – CS

Mean age 53 y

Female

NM

RIA

136

17.7

11.08

Paul et al. [63]

2008

India

Urban

Community - CS

50 y or above

Female

NM

RIA

150

20.85

8.63

Srimani et al. [64]

2017

India

Rural

Community - CS

45–70 y

Female

NM

EIA

222

20

NM

Harinarayan et al. [65]

2004

India

NM

Community - CS

Mean age 54 y

Female

NM

RIA

164

14.6

7

Agarwal et al. [66]

2013

India

Urban

Hospital - RCT

40–73 y

Female

High

RIA

92

13.43

8.67

Mitra et al. [67]

2016

India

NM

Hospital – CS

45–52 y

Female

NM

CLIA

64

19.5

18.92

Agarwal et al. [68]

2014

India

NM

Hospital – CS

Mean age 56.3 y

Female

NM

CK

71

12.73

7.63

Dixit et al. [69]

2018

India

NM

Hospital – CS

Mean age 56.4 y

Female

NM

RIA

334

12.95

8.08

Kadam et al. [70]

2010

India

Urban

Hospital – CS

40–75 y

Female

Both

RIA

172

10.22

5.68

Mahmood et al. [71]

2017

Bangladesh

Both

Community - CC

20–40 y

Female

Lower

CMIA

80

18.3

2.5

Islam et al. [72]

2007

Bangladesh

Urban

Community - CS

18–36 y

Female

Lower

EIA

200

14.68

4.48

Islam et al. [73]

2006

Bangladesh

Urban

Community - CS

18–60 y

Female

NM

RIA

66

12.3

4.52

Islam et al. [74]

2002

Bangladesh

Both

Community - CS

16–40 y

Female

Both

RIA

189

16.04

NM

Acherjya et al. [75]

2019

Bangladesh

Both

Hospital – CS

10–70 y

Both

NM

RAIA

160

18.6

6.59

Mubashir et al. [76]

2017

Pakistan

NM

Hospital – CC

20–70 y

Both

NM

AMK

345

16.1

11.7

Junaid et al. [77]

2016

Pakistan

NM

Hospital – CC

15–56 y

Both

Both

ELISA

112

17.32

NM

Roomi et al. [78]

2015

Pakistan

NM

Hospital – CS

18–40 y

Both

Both

EIA

88

8.44

0.49

Junaid et al. [79]

2015

Pakistan

NM

Community - CS

15–50 y

Female

Both

EIA

215

16.6

13.8

Sheikh et al. [80]

2012

Pakistan

Urban

Community - CS

30–80 y

Both

Both

RIA

300

18.8

NM

Mehboobali et al. [81]

2015

Pakistan

NM

Community - CS

18–60 y

Both

Lower

ECLIA

858

20.63

7.25

Mansoor et al. [82]

2010

Pakistan

Urban

Hospital – CS

20–75 y

Both

NM

RIA

123

16.44

3.78

Mustafa et al. [83]

2018

Pakistan

Both

Hospital – CS

18–37 y

Female

Both

CMIA

67

8.348

3.076

Rehman et al. [28]

2018

Pakistan

NM

Hospital – CS

25–55 y

Male

NM

NM

313

30.426

5.83

Khan et al. [84]

2019

Pakistan

Urban

Hospital – CS

Median age 20 y

Both

NM

CLIA

167

12.1

8.81

Nadeem et al. [29]

2018

Pakistan

NM

Community - CS

19–25 y

Both

NM

NM

221

9.8

8.7

Iqbal et al. [85]

2019

Pakistan

NM

Hospital – CS

19–69 y

Both

Both

CK

226

15

10.7

Mahmood et al. [86]

2009

Pakistan

NM

Hospital – CS

16–62 y

Both

NM

ECLIA

244

15.65

9.91

Afsar et al. [30]

2014

Pakistan

NM

Hospital – CS

16–80 y

Both

NM

NM

376

22.11

8.56

Kumar et al. [31]

2016

Pakistan

NM

Hospital – CS

Mean age 40.2 y

Both

NM

NM

160

32

6.6

Sharif et al. [87]

2013

Pakistan

NM

Hospital – CC

20–40 y

Female

Both

ELISA

60

11.04

8.44

Khan et al. [88]

2012

Pakistan

Both

Community - CS

18 y or above

Female

Both

ECLIA

305

8.708

8.664

Dar et al. [89]

2012

Pakistan

Urban

Community - CS

18–48 y

Female

NM

ECLIA

174

15.32

6.16

Meyer et al. [90]

2007

Sri Lanka

Urban

Community - CS

30–60 y

Both

NM

RIA

196

21.68

NM

Haugen et al. [91]

2016

Nepal

Urban

Community - CS

17–44 y

Female

NM

LCMS

500

18.96

6.56

Sherchand et al. [92]

2018

Nepal

NM

Hospital – CS

18 y or above

Both

NM

CLIA

300

19

NM

  1. Abbreviations: RCT Randomized Control Trial, CC Case Control, CS Cross Sectional, RIA Radio Immune assay, LCMS Liquid chromatography tandem mass spectroscopy, CLIA Chemiluminiscence immunoassay, CMIA Chemiluminiscent micro particle immune assay, EIA Enzyme Immunoassay, RAIA Random access Immunoassay, AMK Automated Kit, ELISA Enzyme Linked Immune Sorbent Assay, ECLIA Electrochemiluminiscence Immunoassay, Commercial Kits CK, NM Not Mention, y Year