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Table 3 Participant Diagnosis Patterns, by Disease Severity (based on genotype). As reported via survey by parent

From: Diagnosis patterns of sickle cell disease in Ghana: a secondary analysis

Variable

Severe SCD (n = 235)

Mild SCD (n = 116)

Age of SCD Diagnosis (p = 0.009)

 0–6 months old

30 (12.7%)

9 (7.8%)

 7–11 months old

15 (6.3%)

4 (3.5%)

 1–2 years old

44 (18.6%)

12 (10.3%)

 3–4 years old

31 (13.1%)

11 (9.5%)

 5–10 years old

64 (27.0%)

37 (31.9%)

 11–14 years old

27 (11.4%)

14 (12.1%)

 15+ years old

26 (11.0%)

29 (25.0%)

No missing data

  

Mechanism of SCD Diagnosis (p = 0.132)

  “Blood test…”

  For pain crisis

   At the hospital/ER

105 (46.1%)

63 (55.3%)

   At the pediatrician’s office

43 (18.9%)

14 (12.3%)

  Because child in family had SCD

15 (6.6%)

11 (9.7%)

  At birth (newborn screen)

15 (6.6%)

4 (3.5%)

  For another illness (not pain crisis)

41 (18.0%)

14 (12.3%)

 Other

9 (4.0%)

8 (7.0%)

Missing diagnosis mechanism = 11

  

Age of First Pain Crisis (p = 0.047)

 0–6 months old

14 (7.3%)

4 (4.1%)

 7–11 months old

3 (1.6%)

0 (0%)

 1–2 years old

62 (32.3%)

17 (17.4%)

 3–4 years old

18 (9.4%)

14 (14.3%)

 5–10 years old

58 (30.2%)

39 (39.8%)

 11–14 years old

16 (8.3%)

8 (8.2%)

 15+ years old

21 (10.9%)

16 (16.3%)

Missing first pain crisis = 64

  
  1. ER Emergency room
  2. SCD Sickle cell disease
  3. Severe SCD: Hb SS; Hb S Beta Thalassemia-zero
  4. Mild SCD: Hb SC; Hb S Beta Thalassemia-plus; Other
  5. Fisher’s exact used where individual cells < 5