Skip to main content

Table 3 Sub-group analyses: Associations between MMC and STI outcomes among men in the HIPSS study

From: Association of medical male circumcision and sexually transmitted infections in a population-based study using targeted maximum likelihood estimation

HIV PR 95% CI HSV-2 PR (95% CI)
Subgroup 1: Coinfected with at least one other STI
 unadjusted 0.624 (0.513, 0.760) 0.513 0.760 unadjusted 0.754 (0.657, 0.865)
 TMLE 0.713 (0.630, 0.807) 0.630 0.807 TMLE 0.916 (0.849, 0.987)
 PSFM 0.763 (0.609, 0.956) 0.609 0.956 PSFM 0.896 (0.737, 1.090)
 IPTW 0.770 (0.629, 0.943) 0.629 0.943 IPTW 0.902 (0.808, 1.008)
Subgroup 2: Not Coinfected with any other STI
 unadjusted 0.256 (0.109, 0.599) 0.109 0.599 unadjusted 0.707 (0.574, 0.869)
 TMLE 0.419 (0.248, 0.709) 0.248 0.709 TMLE 1.042 (0.918, 1.183)
 PSFM 0.272 (0.097, 0.763) 0.097 0.763 PSFM 0.879 (0.678, 1.141)
 IPTW 0.309 (0.143, 0.666) 0.143 0.666 IPTW 0.887 (0.705, 1.115)
  1. Abbreviations: PR Prevalence ratio, TMLE Targeted maximum likelihood estimation, IPTW Inverse probability of treatment weighting, PSFM Propensity score full matching
  2. 11 men were missing for HSV-2. Bolded PRs were not significant at the 5% level