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Table 4 ConQual summary of the findings

From: Experience of chronic noncommunicable disease in people living with HIV: a systematic review and meta-aggregation of qualitative studies

Synthesized Findings

Type of Research

Dependability

Credibility

ConQual Score

1. Although the current healthcare systems have many barriers preventing PLWH with NCDs from accessing both HIV and NCD care, they can receive resources and knowledge through healthcare providers.

Qualitative

Downgrade 1 level

–

Medium

2. The factors that can affect care continuity and treatment adherence for both HIV and NCDs among PLWH include the individual physical, mental, and financial statuses of PLWH; their relationships with clinicians; and fragmented healthcare systems.

Qualitative

Downgrade 1 level

Downgrade 1 level

Low

3. PLWH with NCDs have long-term physical and psychological manifestations of disease. Psychological manifestations are severe and prevalent when PLWH are informed that they have NCDs. Some changes, including changes in appearance and sexual function, can affect individuals’ daily lives, especially among women living with HIV and NCDs.

Qualitative

Downgrade 1 level

Downgrade 1 level

Low

4. Having more chronic conditions implies more medical costs for PLWH. The more severe the financial hardship of PLWH, the more negatively it affects their employment and family relationships.

Qualitative

Downgrade 1 level

–

Medium

5. PLWH with NCDs experience double stigma toward their HIV and chronic conditions, which may exacerbate their perceived discrimination and lead to social and physical isolation.

Qualitative

Downgrade 1 level

–

Medium

6. PLWH with NCDs have high levels of polypharmacy burden for both ART and other medications. This population has difficulty maintaining high medication adherence due to medication fatigue, side effects, and the large numbers of pills to be taken. PLWH with NCDs may spontaneously use some strategies individually or collectively to achieve high levels of medication adherence.

Qualitative

Downgrade 1 level

Downgrade 1 level

Low

7. Some PLWH with NCDs consider hypertension and cancer more concerning conditions than HIV. However, they still describe the ability of HIV to hibernate. Having NCDs may mask concerns regarding HIV and HIV-positive experiences, which can reinforce the self-management of NCDs.

Qualitative

Downgrade 1 level

–

Medium

8. While facing HIV with NCDs, PLWH can develop positive coping strategies to accept the realities of living with multiple chronic conditions.

Qualitative

Downgrade 1 level

Downgrade 1 level

Low

9. Some PLWH living with chronic diseases struggle with new daily routines, emotional difficulties, and family issues. In extreme cases, PLWH may have suicidal ideation when experiencing high pressure.

Qualitative

Downgrade 1 level

–

Medium