Predictor | Readmitted (N = 682, col % or median (IQR)) | Not readmitted (N = 3212, col % or median (IQR)) | Univariate SHR (95% CI) | Multivariate SHR (95% CI) | p value |
---|---|---|---|---|---|
Sitea - Mbale | 278 (41%) | 1203 (37%) | 1.00 | 1.00 | 0.25 |
Blantyre | 53 (8%) | 402 (13%) | 0.61 (0.45–0.82) | 0.80 (0.57–1.12) | |
Mulago | 136 (20%) | 776 (24%) | 0.79 (0.65–0.97) | 0.82 (0.65–1.03) | |
Soroti | 215 (32%) | 831 (26%) | 1.08 (0.90–1.29) | 0.97 (0.79–1.19) | |
Age at primary admission (per year younger)a | 38.0 (17.0, 60.0) | 34.0 (17.0, 62.0) | 1.01 (0.98–1.03) | 1.07 (1.03–1.10) | < 0.001 |
HIV positivea | 26 (4%) | 81 (3%) | 1.52 (1.02–2.28) | 2.48 (1.63–3.78) | < 0.001 |
Sickle status - AA | 458 (67%) | 2243 (70%) | 1.00 | 1.00 | 0.01 |
AS | 25 (4%) | 99 (3%) | 1.23 (0.82–1.84) | 1.16 (0.75–1.81) | |
SS, unknown at discharge | 122 (18%) | 486 (15%) | 1.15 (0.94–1.39) | 0.95 (0.76–1.20) | |
SS, known at discharge | 73 (11%) | 353 (11%) | 0.98 (0.77–1.25) | 0.62 (0.46–0.82) | |
Two or more hospital admissions in the last year before primary admissiona | 250 (37%) | 651 (20%) | 2.05 (1.76–2.40) | 1.44 (1.19–1.74) | < 0.001 |
Received blood transfusion ever, prior to this illnessa | 341 (50%) | 939 (29%) | 2.17 (1.87–2.52) | 1.48 (1.13–1.93) | 0.005 |
History of cough at primary admissiona | 459 (67%) | 1973 (61%) | 1.27 (1.08–1.49) | 1.13 (0.95–1.35) | 0.16 |
Indrawing on admissiona | 118 (17%) | 378 (12%) | 1.51 (1.24–1.84) | 1.36 (1.09–1.71) | 0.01 |
Splenomegaly on admissiona - Not palpable | 363 (53%) | 2132 (66%) | 1.00 | 1.00 | 0.01 |
Enlarged | 248 (36%) | 884 (28%) | 1.57 (1.33–1.84) | 1.26 (1.06–1.50) | |
Gross | 71 (10%) | 190 (6%) | 2.02 (1.57–2.61) | 1.47 (1.10–1.97) | |
Diarrhoea on admission | 68 (10%) | 437 (14%) | 0.72 (0.56–0.92) | 0.71 (0.54–0.93) | 0.01 |
Received oral antimalarials in last week before primary admission | 359 (53%) | 1529 (48%) | 1.21 (1.04–1.41) | 1.08 (0.92–1.27) | 0.36 |
Malaria positive at primary admission, no previous blood transfusion | 195 (29%) | 1533 (48%) | 0.65 (0.52–0.81) | 0.60 (0.47–0.76) | < 0.001 |
Malaria positive at primary admission, previous blood transfusion | 209 (31%) | 539 (17%) | 1.73 (1.40–2.14) | 1.58 (1.22–2.04) | < 0.001 |
Randomised > 24 h after admissiona | 37 (5%) | 131 (4%) | 1.28 (0.92–1.77) | 1.36 (0.96–1.93) | 0.08 |
Strataa - TRACT A | 452 (66%) | 1884 (59%) | 1.00 | 1.00 | 0.14 |
TRACT B, immediate transfusion | 122 (18%) | 655 (20%) | 0.78 (0.64–0.95) | 0.93 (0.74–1.17) | |
TRACT B, triggered transfusion | 69 (10%) | 312 (10%) | 0.91 (0.71–1.17) | 1.05 (0.79–1.40) | |
TRACT B, no transfusion | 39 (6%) | 361 (11%) | 0.48 (0.35–0.67) | 0.67 (0.47–0.96) | |
Blood pack age (per week older)a | 12.0 (7.0, 20.0) | 12.0 (7.0, 17.0) | 1.10 (1.03–1.18) | 1.07 (0.99–1.15) | 0.08 |
Length of stay (per day longer)a | 3.0 (2.0, 5.0) | 3.0 (2.0, 4.0) | 1.05 (1.03–1.07) | 1.03 (1.00–1.06) | 0.04 |
Missed dose of MVMM, iron folate or cotrimoxazole by 28 days | 245 (36%) | 925 (29%) | 1.35 (1.15–1.58) | 1.43 (1.21–1.69) | < 0.001 |