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Table 2 Clinical Characteristics of COVID-19 Hospitalized Patients (n = 3536), by Race and Ethnicity, at Houston Methodist through July 18th, 2020

From: Disparities in COVID-19 hospitalizations and mortality among black and Hispanic patients: cross-sectional analysis from the greater Houston metropolitan area

 

Non-Hispanic White

(n = 966)

Non-Hispanic

Black

(n = 937)

Non-Hispanic

(n = 2115)

Hispanic

(n = 1366)

Demographic Characteristics and Comorbidity Index – n (%)

Age – mean (SD)

65.0 (17.6)

59.0 (16.4) a

62.1 (17.3)

54.2 (16.3) a

Female

437 (45.2)

513 (54.7) a

1030 (48.7)

642 (47.0)

Insurance Type

 Commercial

301 (31.2)

332 (35.4) a

718 (33.9)

447 (32.7) a

 Medicare

478 (49.5)

388 (41.4)

956 (45.2)

377 (27.6)

 Medicaid

27 (2.8)

50 (5.3)

82 (3.9)

122 (8.9)

 Self-Pay

90 (9.3)

122 (13.0)

231 (10.9)

386 (28.3)

 Other

70 (7.2)

45 (4.8)

128 (6.1)

34 (2.5)

Household Income (USD), Median (IQR)

68,318 (56,974 – 94,829.3)

56,974 (44,422 – 70,658) a

65,805 (48,790 – 86,034)

56,288 (44,422 – 70,324) a

Population Density (per square mile), Median (IQR)

2493.9 (812.2–4081.3)

3256.8 (1925.8–4789.7) a

2849.1 (1439.1–4304.3)

3513.1 (1823.2–4988.2) a

CCI Total, Median (IQR)

5 (2–8)

3 (1–7) a

4 (2–7)

2 (1–4) a

Vital Signs at Hospital Admission – n (%)

 SBP (mmHg) – mean (SD)

133.8 (19.3)

136.0 (20.8) a

134.4 (19.9)

131.7 (18.9) a

 DBP (mmHg) – mean (SD)

71.5 (9.3)

74.1 (10.6) a

72.6 (9.9)

72.2 (9.3)

 Respiratory Rate ≥ 24 breath / min

172 (17.8)

162 (17.3)

384 (18.2)

350 (25.6) a

 Temperature ≥ 38 °C

31 (3.2)

80 (8.5) a

129 (6.1)

89 (6.5)

 Oxygen Saturation < 94%

176 (18.2)

111 (11.8) a

335 (15.8)

262 (19.2) a

Laboratory Parameters – n (%)b

 WBC count < 4000/μl

79/964 (8.2)

63/935 (6.7)

159/2111 (7.5)

74/1361 (5.4) a

 Lymphocytes < 20%

665/964 (69.0)

554/934 (59.3) a

1383/2110 (65.5)

938/1360 (69.0) a

 Platelet count < 150,000/μl

148/964 (15.4)

110/935 (11.8) a

284/2111 (13.5)

145/1361 (10.7) a

 B-natriuretic peptide > 100 pg/ml,

296/696 (42.5)

213/646 (33.0) a

566/1500 (37.7)

245/954 (25.7) a

 Procalcitonin > 0.25 ng/ml

149/319 (46.7)

189/327 (57.8) a

375/726 (51.7)

248/526 (47.1)

 Troponin ≥0.06 ng/ml

206/607 (33.9)

224/618 (36.2)

475/1364 (34.8)

186/633 (29.4) a

 Aspartate aminotransferase > 40 U/l

426/938 (45.4)

467/919 (50.8) a

1029/2068 (49.8)

750/1337 (56.1) a

 Alanine aminotransferase > 40 U/l

322/936 (34.4)

317/917 (34.6)

744/2064 (36.0)

693/1335 (51.9) a

 Total Bilirubin ≥1.2 mg/dl

39/861 (4.5)

43/865 (5.0)

88/1930 (4.6)

40/1254 (3.2)

 C-reactive protein > 8.2 ng/ml

750/802 (93.5)

725/777 (93.3)

1661/1775 (93.6)

1167/1199 (97.3) a

 Ferritin level > 3000 ng/ml

35/803 (4.4)

70/774 (9.0) a

114/1774 (6.4)

65/1228 (5.3)

 D-dimer > 0.5 μg/ml

670/775 (86.5)

681/766 (88.9)

1511/1730 (87.3)

985/1201 (82.0) a

 Creatinine > 1.5 mg/dl

154/956 (16.1)

255/929 (27.4) a

441/2097 (21.0)

159/1346 (11.8) a

 Venous Lactate > 2.2 mmol/l

141/714 (19.7)

122/669 (18.2)

301/1557 (19.3)

191/972 (19.7)

Level of Hospital Care – n (%)

 ICU Stay – n (%)

284 (29.4)

297 (31.7)

655 (31.0)

432 (31.6)

 On Ventilator – n (%)

156 (16.1)

162 (17.3)

361 (17.1)

212 (15.5)

  Days on Ventilator, median (IQR)c

6.7 (2.5–13.3)

6.9 (2.9–15.2)

6.9 (2.8–14.8)

8.0 (3.6–14.3)

Hospital Complications – n (%)

 Pneumonia

600 (62.1)

617 (65.8)

1366 (64.6)

958 (70.1) a

 ARDS

35 (3.6)

51 (5.4)

109 (5.2)

80 (5.9)

 Bronchitis

12 (1.2)

14 (1.5)

27 (1.3)

16 (1.2)

 Lower Respiratory Tract Infection

12 (1.2)

11 (1.2)

24 (1.1)

9 (0.7)

 Acute Renal Injury

229 (23.7)

303 (32.3) a

580 (27.4)

191 (14.0) a

 Acute Hepatic Injury

16 (1.7)

9 (1.0)

28 (1.3)

18 (1.3)

 Cardiomyopathy or CHF

151 (15.6)

149 (15.9)

321 (15.2)

96 (7.0) a

 Hypoxic Respiratory Failure

347 (35.9)

330 (35.2)

764 (36.1)

589 (43.1) a

Therapeutics – n (%)

 Hydroxychloroquine

109 (11.3)

123 (13.1)

258 (12.2)

101 (7.4) a

 Ribavirin

33 (3.4)

29 (3.1)

71 (3.4)

31 (2.3)

 Azithromycin

124 (12.8)

150 (16.0)

312 (14.8)

208 (15.2)

 Lopinavir/Ritonavir

12 (1.2)

8 (0.9)

22 (1.0)

2 (0.1) a

 Remdesivir

147 (15.2)

139 (14.8)

333 (15.7)

345 (25.3) a

 Tocilizumab

146 (15.1)

149 (15.9)

354 (16.7)

320 (23.4) a

 Antithrombotic

387 (40.1)

367 (39.2)

830 (39.2)

329 (24.1) a

 Anticoagulants

874 (90.5)

827 (88.3)

1897 (89.7)

1246 (91.2)

 Dexamethasone

389 (40.3)

360 (38.4)

841 (39.8)

681 (49.9) a

Outcomes – n (%)

 Currently Hospitalized

182 (18.8)

171 (18.2)

391 (18.5)

256 (18.7)

 Died

84 (8.7)

58 (6.2) a

164 (7.8)

66 (4.8) a

 Died (among discharged or died)

84/784 (10.7)

58/766 (7.6) a

164/1724 (9.5)

66/1110 (5.9) a

 Died (ICU admits excl. Currently hospitalized)d

60/213 (28.2)

44/209 (21.1) a

124/478 (25.9)

62/304 (20.4) a

 Length of Stay Days – median (IQR)e

7 (3–15)

6 (3–12)

6 (3–13)

5 (3–10)

  1. CCI Charlson Comorbidity Index, IQR Interquartile Range, SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure, WBC White Blood Cell Count, ARDS Acute Respiratory Distress Syndrome, CHF Congestive Heart Failure
  2. a p < 0.05
  3. b Denominator denotes number of non-missing values
  4. c Non-zero ventilator days
  5. d Denominator denotes number of ICU admits
  6. e LOS only for discharged or died
  7. Excluding missing data:
  8. Ethnicity (n = 55)
  9. Median Household Income (n = 34)
  10. Population Density (n = 30)