Non-Hispanic White (n = 966) | Non-Hispanic Black (n = 937) | Non-Hispanic (n = 2115) | Hispanic (n = 1366) | |
---|---|---|---|---|
Demographic Characteristics and Comorbidity Index – n (%) | ||||
Age – mean (SD) | 65.0 (17.6) | 59.0 (16.4) a | 62.1 (17.3) | 54.2 (16.3) a |
Female | 437 (45.2) | 513 (54.7) a | 1030 (48.7) | 642 (47.0) |
Insurance Type | ||||
Commercial | 301 (31.2) | 332 (35.4) a | 718 (33.9) | 447 (32.7) a |
Medicare | 478 (49.5) | 388 (41.4) | 956 (45.2) | 377 (27.6) |
Medicaid | 27 (2.8) | 50 (5.3) | 82 (3.9) | 122 (8.9) |
Self-Pay | 90 (9.3) | 122 (13.0) | 231 (10.9) | 386 (28.3) |
Other | 70 (7.2) | 45 (4.8) | 128 (6.1) | 34 (2.5) |
Household Income (USD), Median (IQR) | 68,318 (56,974 – 94,829.3) | 56,974 (44,422 – 70,658) a | 65,805 (48,790 – 86,034) | 56,288 (44,422 – 70,324) a |
Population Density (per square mile), Median (IQR) | 2493.9 (812.2–4081.3) | 3256.8 (1925.8–4789.7) a | 2849.1 (1439.1–4304.3) | 3513.1 (1823.2–4988.2) a |
CCI Total, Median (IQR) | 5 (2–8) | 3 (1–7) a | 4 (2–7) | 2 (1–4) a |
Vital Signs at Hospital Admission – n (%) | ||||
SBP (mmHg) – mean (SD) | 133.8 (19.3) | 136.0 (20.8) a | 134.4 (19.9) | 131.7 (18.9) a |
DBP (mmHg) – mean (SD) | 71.5 (9.3) | 74.1 (10.6) a | 72.6 (9.9) | 72.2 (9.3) |
Respiratory Rate ≥ 24 breath / min | 172 (17.8) | 162 (17.3) | 384 (18.2) | 350 (25.6) a |
Temperature ≥ 38 °C | 31 (3.2) | 80 (8.5) a | 129 (6.1) | 89 (6.5) |
Oxygen Saturation < 94% | 176 (18.2) | 111 (11.8) a | 335 (15.8) | 262 (19.2) a |
Laboratory Parameters – n (%)b | ||||
WBC count < 4000/μl | 79/964 (8.2) | 63/935 (6.7) | 159/2111 (7.5) | 74/1361 (5.4) a |
Lymphocytes < 20% | 665/964 (69.0) | 554/934 (59.3) a | 1383/2110 (65.5) | 938/1360 (69.0) a |
Platelet count < 150,000/μl | 148/964 (15.4) | 110/935 (11.8) a | 284/2111 (13.5) | 145/1361 (10.7) a |
B-natriuretic peptide > 100 pg/ml, | 296/696 (42.5) | 213/646 (33.0) a | 566/1500 (37.7) | 245/954 (25.7) a |
Procalcitonin > 0.25 ng/ml | 149/319 (46.7) | 189/327 (57.8) a | 375/726 (51.7) | 248/526 (47.1) |
Troponin ≥0.06 ng/ml | 206/607 (33.9) | 224/618 (36.2) | 475/1364 (34.8) | 186/633 (29.4) a |
Aspartate aminotransferase > 40 U/l | 426/938 (45.4) | 467/919 (50.8) a | 1029/2068 (49.8) | 750/1337 (56.1) a |
Alanine aminotransferase > 40 U/l | 322/936 (34.4) | 317/917 (34.6) | 744/2064 (36.0) | 693/1335 (51.9) a |
Total Bilirubin ≥1.2 mg/dl | 39/861 (4.5) | 43/865 (5.0) | 88/1930 (4.6) | 40/1254 (3.2) |
C-reactive protein > 8.2 ng/ml | 750/802 (93.5) | 725/777 (93.3) | 1661/1775 (93.6) | 1167/1199 (97.3) a |
Ferritin level > 3000 ng/ml | 35/803 (4.4) | 70/774 (9.0) a | 114/1774 (6.4) | 65/1228 (5.3) |
D-dimer > 0.5 μg/ml | 670/775 (86.5) | 681/766 (88.9) | 1511/1730 (87.3) | 985/1201 (82.0) a |
Creatinine > 1.5 mg/dl | 154/956 (16.1) | 255/929 (27.4) a | 441/2097 (21.0) | 159/1346 (11.8) a |
Venous Lactate > 2.2 mmol/l | 141/714 (19.7) | 122/669 (18.2) | 301/1557 (19.3) | 191/972 (19.7) |
Level of Hospital Care – n (%) | ||||
ICU Stay – n (%) | 284 (29.4) | 297 (31.7) | 655 (31.0) | 432 (31.6) |
On Ventilator – n (%) | 156 (16.1) | 162 (17.3) | 361 (17.1) | 212 (15.5) |
Days on Ventilator, median (IQR)c | 6.7 (2.5–13.3) | 6.9 (2.9–15.2) | 6.9 (2.8–14.8) | 8.0 (3.6–14.3) |
Hospital Complications – n (%) | ||||
Pneumonia | 600 (62.1) | 617 (65.8) | 1366 (64.6) | 958 (70.1) a |
ARDS | 35 (3.6) | 51 (5.4) | 109 (5.2) | 80 (5.9) |
Bronchitis | 12 (1.2) | 14 (1.5) | 27 (1.3) | 16 (1.2) |
Lower Respiratory Tract Infection | 12 (1.2) | 11 (1.2) | 24 (1.1) | 9 (0.7) |
Acute Renal Injury | 229 (23.7) | 303 (32.3) a | 580 (27.4) | 191 (14.0) a |
Acute Hepatic Injury | 16 (1.7) | 9 (1.0) | 28 (1.3) | 18 (1.3) |
Cardiomyopathy or CHF | 151 (15.6) | 149 (15.9) | 321 (15.2) | 96 (7.0) a |
Hypoxic Respiratory Failure | 347 (35.9) | 330 (35.2) | 764 (36.1) | 589 (43.1) a |
Therapeutics – n (%) | ||||
Hydroxychloroquine | 109 (11.3) | 123 (13.1) | 258 (12.2) | 101 (7.4) a |
Ribavirin | 33 (3.4) | 29 (3.1) | 71 (3.4) | 31 (2.3) |
Azithromycin | 124 (12.8) | 150 (16.0) | 312 (14.8) | 208 (15.2) |
Lopinavir/Ritonavir | 12 (1.2) | 8 (0.9) | 22 (1.0) | 2 (0.1) a |
Remdesivir | 147 (15.2) | 139 (14.8) | 333 (15.7) | 345 (25.3) a |
Tocilizumab | 146 (15.1) | 149 (15.9) | 354 (16.7) | 320 (23.4) a |
Antithrombotic | 387 (40.1) | 367 (39.2) | 830 (39.2) | 329 (24.1) a |
Anticoagulants | 874 (90.5) | 827 (88.3) | 1897 (89.7) | 1246 (91.2) |
Dexamethasone | 389 (40.3) | 360 (38.4) | 841 (39.8) | 681 (49.9) a |
Outcomes – n (%) | ||||
Currently Hospitalized | 182 (18.8) | 171 (18.2) | 391 (18.5) | 256 (18.7) |
Died | 84 (8.7) | 58 (6.2) a | 164 (7.8) | 66 (4.8) a |
Died (among discharged or died) | 84/784 (10.7) | 58/766 (7.6) a | 164/1724 (9.5) | 66/1110 (5.9) a |
Died (ICU admits excl. Currently hospitalized)d | 60/213 (28.2) | 44/209 (21.1) a | 124/478 (25.9) | 62/304 (20.4) a |
Length of Stay Days – median (IQR)e | 7 (3–15) | 6 (3–12) | 6 (3–13) | 5 (3–10) |