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Table 2 Event and event rates by the presence of osteoarthritis and/or diabetes among older adults with non-valvular atrial fibrillationa: Hawaii Medicare data 2009–2017

From: The impact of diabetes and osteoarthritis on the occurrence of stroke, acute myocardial infarction, and heart failure among older adults with non-valvular atrial fibrillation in Hawaii: a retrospective observational cohort study

  Total Without DM/OA
n = 11,721
With DM
n = 4659
With OA
n = 1978
With DM/OA
n = 1230
Stroke
 Diagnosis, n 2966 1630 837 315 184
 Days, medianb 580.0 534.0 653.0 656.5 692.5
 Rate, per 1000 p-yr (95% CI) 60.5 (58.3–62.7) 56.6 (53.8–59.4)c 68.9 (64.3–73.7) 63.2 (56.4–70.5) 59.6 (51.3–68.9)
Acute myocardial infarction
 Diagnosis, n 1287 603 438 128 118
 Days, medianb 676.5 631.0 715.0 739.5 739.0
 Rate, per 1000 p-yr (95% CI) 24.3 (23.0–25.6) 19.2 (17.7–20.8) c,d,e 33.6 (30.5–36.9) d 23.7 (19.8–28.2) e 36.5 (30.2–43.7)
Heart failure
 Diagnosis, n 7871 4272 2254 764 581
 Days, medianb 308.0 305.0 289.0 366.5 331.5
 Rate, per 1000 p-yr (95% CI) 207.6 (203.1–212.3) 184.8 (179.3–190.4) c,d,e 260.0 (249.4–271.0) d 192.4 (179.0–206.6) e 269.6 (248.1–292.5)
  1. a Older adults with non-valvular atrial fibrillation had no stroke, acute myocardial infarction, and heart failure at baseline (n = 19,588). b Follow-up duration in days. c,d,e A significant difference between the corresponding group in the column and the cDM, dOA, or eDM/OA group (p < 0.05). Abbreviations: per 1000 p-yr per 1000 person-years; CI  confidence interval