Spatio-temporal epidemiology of the tuberculosis incidence rate in Iran 2008 to 2018

Table 4 Spatio-temporal variations of TB and SPPTB in areas with higher trends, Iran, March 2008 to March 2018

Type of disease	Window size	Cluster name	Location IDs	Coordinates / radius	Population	Number of cases	Expected cases	Annual cases / 100,000	OE	RR	Inside time trend (annual decrease)	Outside time trend (annual decrease)	LLR	P-value
TB	25%	1	26, 7	(36.380600 N, 52.386100 E) / 113.98 km	18,063,139	21,911	23,660.62	12.1	0.93	0.91	0.130%	3.043%	62.05	0.001
		2	12, 8, 22, 25	(31.438500 N, 49.012100 E) / 231.32 km	7,960,272	10,836	10,427.04	13.6	1.04	1.04	0.471%	2.652%	19.51	0.001
		3	24	(37.253500 N, 49.490400 E) / 0 km	2,498,200	4834	3272.35	19.4	1.48	1.50	0.360%	2.549%	16.38	0.001
	35%	1	7, 26, 18, 17, 27, 24, 29	(35.666400 N, 51.475800 E) / 274.03 km	26,168,650	31,939	34,277.90	12.2	0.93	0.90	0.445%	3.323%	77.32	0.001
	35%	2	12, 8, 22, 25	(31.438500 N, 49.012100 E) / 231.32 km	7,960,272	10,836	10,427.04	13.6	1.04	1.04	0.471%	2.652%	19.51	0.001
	50%	1	29, 27, 25, 17, 19, 13, 21, 18, 5, 7, 24, 8, 26, 12	(34.885200 N, 48.610600 E) / 384.83 km	38,534,499	47,909	50,475.74	12.4	0.95	0.90	0.891%	3.795%	91.30	0.001
SPPTB	25%	1	26, 7	(36.380600 N, 52.386100 E) / 113.98 km	18,063,139	10,434	11,830.66	5.8	0.88	0.85	0.083%	3.111%	32.34	0.001
	35%	1	7, 26, 18, 17, 27, 24, 29	(35.666400 N, 51.475800 E) / 274.03 km	26,168,650	15,652	17,139.46	6.0	0.91	0.87	0.487%	3.391%	38.96	0.001
	50%	1	29, 27, 25, 17, 19, 13, 21, 18, 5, 7, 24, 8, 26, 12	(34.885200 N, 48.610600 E) / 384.83 km	38,534,499	23,340	25,238.62	6.1	0.92	0.86	0.702%	4.035%	59.98	0.001

A cluster is statistically significant when its log likelihood ratio is greater than the critical value, which is, for significance level: (Gumbel Critical Values: 0.00001: 13.417707 and 0.0001: 11.182490)