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Table 1 Study Characteristics

From: Transparent reporting of recruitment and informed consent approaches in clinical trials recruiting children with minor parents in sub-Saharan Africa: a secondary analysis based on a systematic review

# Author Country Health condition Intervention Study Population size Study population age range
1 Achonduh et al. (2012) [26] Cameroon Malaria Dietary supplements (vitamin A, zinc) and antimalarials (artesunate-amodiaquine) 100 6–24 months
2 Adegbehingbe et al. (2010) [27] Nigeria Clubfoot Surgical methods (Ponseti method and extensive soft tissue surgery) 105 0–adult
3 Afolabi et al. (2013) [28] The Gambia HIV Vaccine 48 0–9 months
4 Aluka et al. (2013) [29] Nigeria Fever Coldwater sponging, oral paracetamol 88 12–120 months
5 Amadi et al. (2002) [30] Zambia Diarrhoea and malnutrition (cryptosporidiosis) Antiparasitic (nitazoxanide) 96 1–7 years
6 Arimond et al. (2017) [31] Ghana, Malawi, Burkina Faso Undernutrition Dietary supplements (lipid-based) 2622, 1318, 1093, 625 0–18 months
7 Armah et al. (2010) [32] Ghana, Kenya, Mali Gastroenteritis (Rotavirus) Vaccine 5468 4–12 weeks
8 Armah et al. (2013) [33] Ghana Gastroenteritis (Rotavirus) Vaccine 998 0–29 days
9 Christofides et al. (2006) [34] Ghana Anaemia (Iron deficiency) Dietary supplement (iron) 133 6–18 months
10 Corbett et al. (2010) [35] Malawi HIV Antiretrovirals (lamivudine, stavudine, nevirapine) 18 1–13 years
11 Egere et al. (2012) [36] The Gambia Pneumonia (Streptococcus pneumoniae) Vaccine 328 2–30 months
12 Gilliams et al. (2014) [37] Malawi Malaria Antimalarials (chloroquine-azithromycin) 320 20–46 months
13 Goodhew et al. (2014) [38] Tanzania Trachoma Mass drug administration (azithromycin) 264 1–6 years
14 Hassall et al. (2015) [39] Kenya Malaria Umbilical cord red blood cell transfusion 55 0–6 years
15 Hess et al. (2015) [40] Burkina Faso Undernutrition (Growth stunting) Dietary supplements (lipid-based) 3220 9 months
16 Hesseling et al. (2005) [41] Malawi Burkitt Lymphoma Chemotherapy (vincristine, methotrexate, leucovorin, cyclophosphamide, prednisone) 60 3–16 years
17 Hussey et al. (1990) [42] South Africa Measles Dietary supplement (vitamin A) 189 0–13 years
18 Isanaka (2017) [43] Niger Gastroenteritis (Rotavirus) Vaccine 3508 6–14 weeks
19 Kone et al. (2010) [44] Mali Malaria (Glucose-6-phosphate dehydrogenase deficiency) Antimalarials (artemether-lumefantrine, artesunate-mefloquine) 315 > 1 year
20 Koram et al. (2005) [45] Ghana Malaria Antimalarials (amodiaquine-artesunate, artemether-lumefantrine, sulfadoxine-pyrimethamine, chloroquine) 168 6–59 months
21 Madhi et al. (2011) [46] South Africa Childhood diseases (Hepatitis B, diphtheria, tetanus, pertussis, polio, Haemophilus influaenzae) Vaccines 715 0–3 days
22 Madhi et al. (2012) [47] South Africa, Malawi Gastroenteritis (Rotavirus) Vaccine 3168 6–16 weeks
23 Maka et al. (2015) [48] Cameroon Malaria Antimalarials (artesunate, quinine) 238 3 months–15 years
24 Mangani et al. (2015) [49] Malawi Undernutrition (Growth stunting) Dietary supplements (lipid-based, corn-soy blend) 840 5.5–6.5 months
25 Meremikwu et al. (2006) [50] Nigeria Malaria Antimalarials (artemether-lumefantrine, artesunate-amodiaquine) 119 6–59 months
26 Meremikwu et al. (2016) [51] Nigeria Malaria Antimalarials (artesunate-amodiaquine, dihydroartemisinin-piperaquine, artemether-lumefantrine) 493 6–59 months
27 Michael et al. (2010) [52] Nigeria Malaria Antimalarials (artemether-lumefantrine, artesunate-amodiaquine) 193 12–132 months
28 Ngasala et al. (2011) [53] Tanzania Malaria Antimalarials (artemether-lumefantrine) 300 3–59 months
29 Nji et al. (2015) [54] Cameroon Malaria Antimalarials (dihydroartemisin-piperaquine, artesunate-amodiaquine vs artemether-lumefantrine) 720 6 months–10 years
30 Nwanyanwu et al. (1996) [55] Malawi Malaria Antimalarials (sulphadoxine-pyrimethamine) 159 0–5 years
31 Phuka et al. (2008) [56] Malawi Undernutrition (Growth stunting) Dietary supplements (fortified spread, micronutrient-fortified maize-soy flour) 182 6–18 months
32 Rahimy et al. (1999) [57] Benin Fever (in Sickle Cell Disease) Antibiotics (outpatient management) 61 0–12 years
33 Robertson et al. (2011) [58] Uganda Perinatal asphyxial encephalopathy Therapeutic hypothermia 36 3 h
34 Roca et al. (2011) [59] The Gambia Pneumococcal disease Vaccine 5441 0–adult
35 Sazawal et al. (2007) [60] Zanzibar Undernutrition (Mortality) Dietary supplement (zinc) 42,546 1–36 months
36 Schellenberg et al. (2001) [61] Tanzania Malaria and anaemia Antimalarials (sulphadoxine-pyrimethamine) alongside routine vaccinations 701 0–1 year
37 Singana et al. (2016) [62] Republic of Congo Malaria Antimalarials (artesunate-amodiaquine, artemether-lumefantrine) 198 < 12 years
38 Sissoko et al. (2016) [63] Guinea Ebola Antiviral (favipiravir) 111 > 1 year
39 Sow et al. (2012) [64] Mali Gastroenteritis (Rotavirus) Vaccine 1960 48 days (median age)
40 Te Water Naude et al. (2000) [65] South Africa Tuberculosis Chemotherapy (isoniazid, rifampin, pyrazinamide) 206 0–14 years
41 The Zinc Against Plasmodium Study Group (2002) [66] Ecuador, Ghana, Tanzania, Uganda, Zambia Malaria Antimalarial and dietary supplement (chloroquine and zinc) 1087 6–60 months
42 Urban et al. (2008) [67] South Africa Nutrition (Infant growth) Dietary supplements (biologically acidified milk, probiotics) 85 0–1 week
43 Waggie et al. (2011) [68] South Africa Polio Vaccine 800 0–30 days
44 Yohannan et al. (2013) [69] Tanzania Trachoma Mass drug administration (azithromycin, tetracycline) 2261 0–5 years