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Table 8 Comparison of estimates of affected newborns with thalassemia disease for Thai populations and migrant workers

From: Feasibility of and barriers to thalassemia screening in migrant populations: a cross-sectional study of Myanmar and Cambodian migrants in Thailand

  Thai (Current study) Thai (Hockham et al., 2019) [27] Thai (Fucharoen et al., 2014) [31] Myanmar (Current study) Cambodian (Current study)
Hb Bart’s hydrops fetalis
 • Affected newborns (cases/1000 birth/year) 0.462 N/A N/A 0.017 0.164
 • Affected newborns in Thailanda (cases/year) 335 423 (CI: 184–761) 833 < 1 (0.18) < 1 (0.23)
Hb H disease (all)
 • Affected newborns (cases/1000 birth/year) 4.885 N/A N/A 1.525 4.759
 • Affected newborns in Thailanda (cases/year) 3540 3172 5600 16 7
 • Deletional Hb H disease (cases/year) 2742 2674 (CI:1296–4491) N/A 16 7
 • Non-deletional Hb H disease (cases/year) 798 498 (CI:237–947) N/A 0 0 (0.1)
Homozygous β-thalassemia
 • Affected newborns (cases/1000 birth/year) 0.202 N/A N/A 0.615 0.010
 • Affected newborns in Thailanda (cases/year) 146 N/A 207 7 < 1 (0.01)
Hb E/β-thalassemia
 • Affected newborns (cases/1000 birth/year) 3.618 N/A N/A 2.872 1.231
 • Affected newborns in Thailanda (cases/year) 2622 N/A 3213 31 2
 • Hb E/β+-thalassemia (cases/year) 1126 N/A N/A 5 0
 • Hb E/β0-thalassemia (cases/year) 1496 N/A N/A 26 2
  1. NA Not available, CI 95% confidence interval
  2. a Estimated numbers of births in Thailand in 2020 are 10,765 and 1418 for Myanmar and Cambodian migrant workers, respectively, and 724,587 for Thai population [28]