Feasibility of and barriers to thalassemia screening in migrant populations: a cross-sectional study of Myanmar and Cambodian migrants in Thailand

Table 2 Common α- and β-globin mutations identified using previously described multiplex PCR-based techniques [24].

No.	Globin gene type	Mutation	Mutation type
1	α-globin	-α^3.7	Single deletion
2		-α^4.2	Single deletion
3		- -^SEA	Double deletion
4		- -^THAI	Double deletion
5		- -^FIL	Double deletion
6		- -^MED	Double deletion
7		-(α)^20.5	Double deletion
8		- -^SIAM	Double deletion^a
9		Initiation codon (ATG > A-G)	Non-deletion
10		Codon 30 (∆GAG)	Non-deletion
11		Codon 59 (GGC > GAC)	Non-deletion
12		Codon 142 (Pakse; TAA > TAT)	Non-deletion
13		Codon 125 (Quang Sze; CTG > CCG)	Non-deletion
14		Codon 142 (Constant Spring; TAA > CAA)	Non-deletion
15	β-globin	nt −28 (A > G)	β⁺
16		Codon 8/9 (+G)	β⁰
17		IVSI-5 (G > C)	β⁺
18		Codon 41/42 (−TTCT)	β⁰
19		Codon 71/72 (+A)	β⁰
20		Codon 17 (A > T)	β⁰
21		IVSI-1 (G > T)	β⁰
22		Codon 26 Hb E (GAG > AAG)	β^E
23		IVSII-654 (C > T)	β⁺
24		Codon 35 (C > A)	β⁰
25		Codon 43 (G > T)	β⁰
26		Codon 26 (G > T)	β⁰
27		Codon 95 (+A)	β⁰
28		Codon 19 (A > G)	β⁺
29		Codon 41 (−C)	β⁰
30		Codon 27/28 (+C)	β⁰

^a The α-globin deletion - -^SIAM was identified using the methodology described in Riolueang et al. 2019 [25].

ISSN: 1471-2458