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Table 2 Common α- and β-globin mutations identified using previously described multiplex PCR-based techniques [24].

From: Feasibility of and barriers to thalassemia screening in migrant populations: a cross-sectional study of Myanmar and Cambodian migrants in Thailand

No. Globin gene type Mutation Mutation type
1 α-globin 3.7 Single deletion
2 4.2 Single deletion
3 - -SEA Double deletion
4 - -THAI Double deletion
5 - -FIL Double deletion
6 - -MED Double deletion
7 -(α)20.5 Double deletion
8 - -SIAM Double deletiona
9 Initiation codon (ATG > A-G) Non-deletion
10 Codon 30 (∆GAG) Non-deletion
11 Codon 59 (GGC > GAC) Non-deletion
12 Codon 142 (Pakse; TAA > TAT) Non-deletion
13 Codon 125 (Quang Sze; CTG > CCG) Non-deletion
14 Codon 142 (Constant Spring; TAA > CAA) Non-deletion
15 β-globin nt −28 (A > G) β+
16 Codon 8/9 (+G) β0
17 IVSI-5 (G > C) β+
18 Codon 41/42 (−TTCT) β0
19 Codon 71/72 (+A) β0
20 Codon 17 (A > T) β0
21 IVSI-1 (G > T) β0
22 Codon 26 Hb E (GAG > AAG) βE
23 IVSII-654 (C > T) β+
24 Codon 35 (C > A) β0
25 Codon 43 (G > T) β0
26 Codon 26 (G > T) β0
27 Codon 95 (+A) β0
28 Codon 19 (A > G) β+
29 Codon 41 (−C) β0
30 Codon 27/28 (+C) β0
  1. a The α-globin deletion - -SIAM was identified using the methodology described in Riolueang et al. 2019 [25].