Table 4 Multivariate logistic regression of the joint effect of hypertension and hyperuricemia for ischemic stroke by sex
From: Combined effect of hypertension and hyperuricemia on ischemic stroke in a rural Chinese population
| Â | Odds Ratio (95%CI) | |||||
|---|---|---|---|---|---|---|
Model 1 | P value | Model 2 | P value | Model 3 | P value | |
Men | ||||||
 HTN (−) HUA (−) | 1 (reference) |  | 1 (reference) |  | 1 (reference) |  |
 HTN (−) HUA (+) | 2.516 (1.055, 6.000) | 0.037 | 3.133 (1.299, 7.556) | 0.011 | 2.890 (1.173, 7.121) | 0.021 |
 HTN (+) HUA (−) | 5.498 (3.409, 8.866) | < 0.001 | 3.777 (2.317, 6.157) | < 0.001 | 3.296 (1.998, 5.437) | < 0.001 |
 HTN (+) HUA (+) | 5.917 (3.276, 10.688) | < 0.001 | 4.827 (2.642, 8.819) | < 0.001 | 4.059 (2.126, 7.751) | < 0.001 |
 P value for interaction |  | 0.007 |  | 0.011 |  | 0.073 |
Women | ||||||
 HTN (−) HUA (−) | 1 (reference) |  | 1 (reference) |  | 1 (reference) |  |
 HTN (−) HUA (+) | 2.136 (0.491, 9.284) | 0.312 | 1.694 (0.387, 7.421) | 0.484 | 1.353 (0.306, 5.991) | 0.691 |
 HTN (+) HUA (−) | 8.956 (5.465, 14.677) | < 0.001 | 5.492 (3.309, 9.114) | < 0.001 | 4.592 (2.740, 7.696) | < 0.001 |
 HTN (+) HUA (+) | 24.254 (13.688, 42.976) | < 0.001 | 12.689 (7.027, 22.912) | < 0.001 | 8.913 (4.726, 16.809) | < 0.001 |
 P value for interaction |  | < 0.001 |  | < 0.001 |  | < 0.001 |