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Table 2 Base case and scenario analysis values and sources

From: Reducing dengue fever cases at the lowest budget: a constrained optimization approach applied to Thailand

Input Base case Scenario analysis
Vaccination target population Paediatric population vaccinated at birth (0–100% coverage) Paediatric population vaccinated at birth (70–100% coverage)
Optimization time horizon 10 years 5 years
Vaccine efficacy 73% 50%, 80%
Time horizon 10 years 5 years
Inpatient costs - $266 DF inpatient direct medical costs [74]
- $566.43 DHF inpatient direct medical costs [70]
- $72.77 inpatient direct non-medical costs [70]
- $54.59 inpatient indirect costs [70]
Unit cost profiles from Fitzpatrick et al. [59]
- $141.55 hospital bed day, primary
- $169.24 hospital bed day, specialist
Outpatient costs - $141.61 outpatient direct medical costs [70]
- $82.20 outpatient direct non-medical costs [70]
- $13.65 outpatient indirect costs [70]
Unit cost profile from Fitzpatrick et al. [59]
- $18.29 ambulatory clinic visit
Cost of ‘un-reported’ cases $12.12 for clinic visit [73] N/ A
Vaccine price per course $40 plus $4 vaccine administration costs $20 plus $4 vaccine administration costs; $60 plus $4 vaccine administration costs
Wolbachia Wolbachia cost per dengue case averted of $1 (i.e. cost of release per person covered of $4.45) Wolbachia cost per person covered of $1 [75,76,77]; Wolbachia cost per person covered of $15.05 [75,76,77] (adjusted to 2013 prices [78])
  1. DF dengue fever, DHF dengue haemorrhagic fever