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Table 2 Base case and scenario analysis values and sources

From: Reducing dengue fever cases at the lowest budget: a constrained optimization approach applied to Thailand

Input

Base case

Scenario analysis

Vaccination target population

Paediatric population vaccinated at birth (0–100% coverage)

Paediatric population vaccinated at birth (70–100% coverage)

Optimization time horizon

10 years

5 years

Vaccine efficacy

73%

50%, 80%

Time horizon

10 years

5 years

Inpatient costs

- $266 DF inpatient direct medical costs [74]

- $566.43 DHF inpatient direct medical costs [70]

- $72.77 inpatient direct non-medical costs [70]

- $54.59 inpatient indirect costs [70]

Unit cost profiles from Fitzpatrick et al. [59]

- $141.55 hospital bed day, primary

- $169.24 hospital bed day, specialist

Outpatient costs

- $141.61 outpatient direct medical costs [70]

- $82.20 outpatient direct non-medical costs [70]

- $13.65 outpatient indirect costs [70]

Unit cost profile from Fitzpatrick et al. [59]

- $18.29 ambulatory clinic visit

Cost of ‘un-reported’ cases

$12.12 for clinic visit [73]

N/ A

Vaccine price per course

$40 plus $4 vaccine administration costs

$20 plus $4 vaccine administration costs; $60 plus $4 vaccine administration costs

Wolbachia

Wolbachia cost per dengue case averted of $1 (i.e. cost of release per person covered of $4.45)

Wolbachia cost per person covered of $1 [75,76,77]; Wolbachia cost per person covered of $15.05 [75,76,77] (adjusted to 2013 prices [78])

  1. DF dengue fever, DHF dengue haemorrhagic fever