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Table 4 Multivariable Cox proportional hazard models reporting hazard ratios for number of removed lymph nodes by cancer site

From: Colon cancer survival differs from right side to left side and lymph node harvest number matter

Factors

Right

Left

n

Person years

HR

(95%CI)

P-value

n

Person years

HR

(95%CI)

P-value

LN harvest

  < 12

58

664.5

1

Β Β 

210

4528.7

1

Β Β 

 12–21

201

4294.4

0.54

(0.40–0.72)

< 0.001

396

9514.8

0.89

(0.76–1.06)

0.194

  > 21

169

4906.2

0.40

(0.30–0.55)

< 0.001

218

5737.9

0.83

(0.69–1.01)

0.064

Stage

 II

167

5547.2

1

Β Β 

327

9970.5

1

Β Β 

 III

261

4317.9

2.01

(1.65–2.44)

< 0.001

497

9810.8

1.59

(1.38–1.83)

< 0.001

  1. The models are adjusted for sex, age, histotype, screening status, stage, and grading
  2. Incident colon cancer cases with lymphadenectomy, stages II and III, Emilia-Romagna, Italy, 2000–2012, follow up until December 31, 2017