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Table 3 Hazard ration (HR) with 95% confidence intervals (95% CI) for cause-specific and all-cause mortality among initially healthy men during 45 years of follow-up, by fasting level of potassium at baseline

From: Fasting serum potassium and long-term mortality in healthy men

Potassium level

Cancer death

Cardiovascular death

Other causes of deathd

All-causee

Age

adjusteda

HR (95% CI)

Multivariable

adjustedb

HR (95% CI)

Age

adjusteda

HR (95% CI)

Multivariable

adjustedb

HR (95% CI)

Age

adjusteda

HR (95% CI)

Multivariable

adjustedb

HR (95% CI)

Age

adjusteda

HR (95% CI)

Multivariable

adjustedb

HR (95% CI)

Per mmol/L

1.90 (1.47–2.46)

1.78 (1.35–2.35)

1.41 (1.13–1.76)

1.37 (1.08–1.74)

1.67 (1.30–2.15)

1.65 (1.26–2.17)

1.62 (1.41–1.87)

1.57 (1.35–1.82)

Per SDc

1.25 (1.14–1.37)

1.22 (1.11–1.35)

1.13 (1.04–1.22)

1.11 (1.03–1.21)

1.20 (1.10–1.31)

1.19 (1.08–1.31)

1.18 (1.13–1.24)

1.17 (1.11–1.23)

Excluding first 10 years of follow-up, per SDc

1.25 (1.14–1.37)

1.23 (1.11–1.36)

1.12 (1.03–1.21)

1.11 (1.02–1.21)

1.20 (1.10–1.31)

1.20 (1.09–1.32)

1.18 (1.12–1.24)

1.17 (1.11–1.24)

Low (≤4.0 mmol/L)

1.00 (ref.)

1.00 (ref.)

1.00 (ref.)

1.00 (ref.)

1.00 (ref.)

1.00 (ref.)

1.00 (ref.)

1.00 (ref.)

Middle (4.1–4.5 mmol/L)

1.64 (1.25–2.16)

1.53 (1.16–2.02)

1.20 (.98–1.48)

1.16 (.94–1.44)

1.17 (.93–1.48)

1.16 (.91–1.48)

1.31 (1.14–1.50)

1.25 (1.09–1.44)

High (≥4.6 mmol/L)

2.00 (1.48–2.70)

1.78 (1.30–2.42)

1.36 (1.08–1.73)

1.24 (.96–1.60)

1.52 (1.17–1.98)

1.41 (1.07–1.86)

1.57 (1.35–1.83)

1.43 (1.22–1.68)

P value for linear trend

 

<.001

 

.10

 

.01

 

<.0001

  1. aCox proportional hazards model assuming different baseline hazards for never, former and present smokers with age as the time scale
  2. bAdditional adjustments for body mass index, systolic blood pressure, fitness, fasting blood glucose, sodium, triglycerides, cholesterol, creatinine and sedimentation rate, all measured at baseline
  3. cThe standard deviations (SD) for potassium was .35 mmol/L
  4. dDeath related to other causes than cancer and cardiovascular disease (see supplementary Table 1 for further details)
  5. eThe all-cause analysis includes 18 men without a specified cause of death