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Table 4 Risk ratios for non-initiation of treatment by demographic and clinical characteristics among individuals seen at the TB Clinic between January 2010 to December 2016. Risk ratios marked with an asterisk (*) are statistically significant. CI= confidence interval

From: Seven-year retrospective study understanding the latent TB infection treatment cascade of care among adults in a low incidence country

Potential Risk Factors

Non-initiators/category total (%)

Unadjusted risk ratio (95% CI)

Adjusted risk ratio (95% CI) n = 568 patientsa

Age, years (per 5-year increase)

-

1.03 (1.00-1.05)

1.06 (1.03-1.08)*

Sex

 Male

213/789 (27.0%)

Reference

Reference

 Female

355/982 (36.2%)

1.34 (1.16-1.54)*

1.28 (1.11-1.47)*

Reason for referral

 Rule out active TB

180/446 (40.4%)

Reference

Reference

 Employment screen

162/430 (37.7%)

0.93 (0.79-1.10)

0.90 (0.76-1.06)

 Health science school screen

42/125 (33.6%)

0.83 (0.63-1.09)

0.84 (0.64-1.11)

 Contact

106/383 (27.7%)

0.68 (0.56-0.85)*

0.71 (0.59-0.86)*

 Immunosuppressive therapy

36/263 (13.7%)

0.34 (0.24-0.47)*

0.30 (0.22-0.41)*

 Immigration surveillance

42/124 (33.9%)

0.84 (0.64-1.10)

0.88 (0.68-1.15)

Year of consultation

 2010

68/259 (26.3%)

0.64 (0.49-0.83)*

0.66 (0.52-0.85)*

 2011

70/269 (26.0%)

0.64 (0.49-0.82)*

0.65 (0.51-0.84)*

 2012

76/235 (32.3%)

0.79 (0.62-1.01)

0.80 (0.63-1.01)

 2013

80/252 (31.7%)

0.78 (0.61-0.99)*

0.78 (0.62-0.98)*

 2014

101/289 (34.9%)

0.85 (0.68-1.07)

0.86 (0.69-1.05)

 2015

81/242 (33.5%)

0.82 (0.65-1.04)

0.88 (0.71-1.11)

 2016

92/225 (40.9%)

Reference

Reference

  1. aModel included age, sex, reason for referral to the TB clinic, and year of consultation