Study by date of publication (effect measure) | Cowie 1994 (IR) [48] | Hnizdo 1998 (RR) [49] (Autopsy grading) | Corbett 1999 (OR) [50] | Corbett 2000 (RR) [51] | Chang 2001 (RR) [52] |
---|---|---|---|---|---|
Adjusted/controlled for. N | Age, date of CXR. N = 1153 | Age, smoking. N = 2255 | Age, HIV, duration employed, dusty job. N = 561 | Age, HIV, duration employed, underground/surface job. N = 4022 | Age, sex, smoking. N = 707 |
Grades or markers of extent of silicosis | None (n = 335): 1.0 (0, 2.0) ILO 1 (n = 418): 2.2 (0.7, 3.6) ILO 2 (n = 355): 2.9 (1.1, 4.6) ILO 3 (n = 45): 6.3 (0, 13.4) | None (n = 577): 1.00 Negligible (n = 310): 1.86 (0.97, 3.58) Slight (n = 196): 2.62 (1.36, 5.03) Moderate/ marked(n = 213): 2.71 (1.41, 5.20) | None (n = 340): 1.00 ILO 0/1 (n = 69): 1.6 (0.86, 2.90) ILO 1/0 (n = 48): 2.8 (1.24, 6.46) ILO > 1/1 (n = 90): 4.9 (2.32, 10.58) | None (n = 2924): 1.00 ILO 0/1 (n = 460): 1.4 (1.0, 2.2) ILO 1/0 (n = 212): 1.8 (1.0, 3.0) ILO 1/1 (n = 156): 2.2 (1.3, 3.7) ILO > 1/1 (n = 197): 2.5 (1.6, 4.0) | PMF (n = 141) vs no PMF (n = 566): 3.78 (2.24, 6.35) |