Table 2 Tuberculosis risk or odds by silicosis relative to no silicosis or general population
First author, year of publication | Study Design | Study /control population(s) | N | Controlling for | Estimate (95% CI) (silicosis vs no silicosis) |
|---|---|---|---|---|---|
Low or intermediate TB burden countries | |||||
 Westerholm 1986 [46] | Cohort | Mining, quarrying and tunneling industries and iron and steel foundries. | 1522 | Occupation, age, calendar year at first silica exposure. | OR 32.99 (4.50, 241.58) a |
 Sherson 1990 [47] | Cohort | Foundry workers, general population | 5579 | (i)None (ii)Age | (i) RR 8.25 (2.81, 24.25) b (ii) SIR 10.00 (2.72, 25.61) |
 Chang 2001 [52] | Cohort | Silicosis register / general population | 707 | Age, gender | SIR 4.9 c |
 Li 2011 [53] | Cohort | End-stage renal disease patients | 49,983 | Age, gender, income,COPD | HR 5.82 (2.17, 15.6) |
 Yarahmadi 2013 [54] | Case control | Community |  | None | OR 4.08 (2.63, 3.62) |
High TB burden countries | |||||
 Cowie 1994 [48] | Cohort | Gold miners | 1153 | Age, date of CXR | RR 2.8 (1.9, 4.1) |
 Hnizdo 1998 [49] | Cohort | Gold miners | 2255 | Age, smoking, cumulative dust exposure | RR 4.18 (2.75, 6.36) |
 Corbett 1999 [50] | Case control | Gold miners | 561 | Age, HIV, duration, employed, dusty job | OR 4.90 (2.32,10.58) |
 Corbett 2000 [51] | Cohort | Gold miners | 4022 | Age, HIV, duration employed, surface/underground | RR 2.2 (1.3, 3.7) d |