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Table 3 Reasons for treatment non-adherence and experienced side effects (prospective participants)

From: Knowledge about tuberculosis, treatment adherence and outcome among ambulatory patients with drug-sensitive tuberculosis in two directly-observed treatment centres in Southwest Nigeria

Variables Response, n (%)  
Any reason(s) for TB treatment non-adherence Yes, 49 (35.0) No, 91 (65.0)
If yes, specific reason(s) (n = 60)*
 Problem of accessibility to healthcare facility 33 (55.0)  
 Too much medicines to take at once 10 (16.7)  
 Size of the tablet being taken 8 (13.3)  
 Dosing schedule/time of medication 6 (10.0)  
 Fear of medication side effects 3 (5.0)  
Did you experienced side effect(s) with the TB medication(s) since commencement? Yes, 67 (47.9) No, 73 (52.1)
If yes, specific side effect(s) experienced (n = 78)*
 Coloured urine 31 (39.7)  
 Allergic skin reactions 16 (20.5)  
 Tiredness 16 (20.5)  
 Neuropathy signs 8 (10.2)  
 Increased appetite 4 (5.1)  
 Increased heartbeat 3 (3.8)  
Did you report the experienced side effect(s) to your physician? (n = 67) Yes, 37 (55.2) No, 30 (44.8)
If yes, what measure(s) was taken by the physician? (n = 37)
 It was expected reaction(s)/side effect(s) 16 (43.2)  
 Prescribed anti-allergy medicine(s) 5 (13.5)  
 Prescribed haematinics 3 (8.1)  
 Prescribed analgesics 3 (8.1)  
 Prescribed antibiotics 2 (5.4)  
 Changed my medication(s) 1 (2.7)  
 Cannot remember the medication(s) prescribed 7 (18.9)  
If No, why don’t you report the experienced side effect(s)? (n = 30)
 Already informed of the side effect(s) 15 (50.0)  
 I intended to report 6 (20.0)  
 I knew it was the medication(s) that caused the side effect 5 (16.7)  
 I purchased antiallergy chlorpheramine on my own 3 (10.0)  
 I purchased a combined antifungal and allergic cream on my own 1 (3.3)  
  1. *multiple response, HRZE Isoniazid (H), Rifampicin (R), Pyrazinamide (Z), Ethambutol (E), TB Tuberculosis, n number