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Table 3 Reasons for treatment non-adherence and experienced side effects (prospective participants)

From: Knowledge about tuberculosis, treatment adherence and outcome among ambulatory patients with drug-sensitive tuberculosis in two directly-observed treatment centres in Southwest Nigeria

Variables

Response, n (%)

 

Any reason(s) for TB treatment non-adherence

Yes, 49 (35.0)

No, 91 (65.0)

If yes, specific reason(s) (n = 60)*

 Problem of accessibility to healthcare facility

33 (55.0)

 

 Too much medicines to take at once

10 (16.7)

 

 Size of the tablet being taken

8 (13.3)

 

 Dosing schedule/time of medication

6 (10.0)

 

 Fear of medication side effects

3 (5.0)

 

 Did you experienced side effect(s) with the TB medication(s) since commencement?

Yes, 67 (47.9)

No, 73 (52.1)

If yes, specific side effect(s) experienced (n = 78)*

 Coloured urine

31 (39.7)

 

 Allergic skin reactions

16 (20.5)

 

 Tiredness

16 (20.5)

 

 Neuropathy signs

8 (10.2)

 

 Increased appetite

4 (5.1)

 

 Increased heartbeat

3 (3.8)

 

 Did you report the experienced side effect(s) to your physician? (n = 67)

Yes, 37 (55.2)

No, 30 (44.8)

If yes, what measure(s) was taken by the physician? (n = 37)

 It was expected reaction(s)/side effect(s)

16 (43.2)

 

 Prescribed anti-allergy medicine(s)

5 (13.5)

 

 Prescribed haematinics

3 (8.1)

 

 Prescribed analgesics

3 (8.1)

 

 Prescribed antibiotics

2 (5.4)

 

 Changed my medication(s)

1 (2.7)

 

 Cannot remember the medication(s) prescribed

7 (18.9)

 

If No, why don’t you report the experienced side effect(s)? (n = 30)

 Already informed of the side effect(s)

15 (50.0)

 

 I intended to report

6 (20.0)

 

 I knew it was the medication(s) that caused the side effect

5 (16.7)

 

 I purchased antiallergy chlorpheramine on my own

3 (10.0)

 

 I purchased a combined antifungal and allergic cream on my own

1 (3.3)

 
  1. *multiple response, HRZE Isoniazid (H), Rifampicin (R), Pyrazinamide (Z), Ethambutol (E), TB Tuberculosis, n number