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Table 4 Association of selected socio-demographic, lifestyle factors, familial history, co-morbidities and dietary habits with acne severity grades and acne scarring grades

From: Modifiable and non-modifiable epidemiological risk factors for acne, acne severity and acne scarring among Malaysian Chinese: a cross-sectional study

Variable

Acne severity

Acne scarring

Unadjusted

Adjusteda

Unadjusted

Adjusteda

 

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

A. Socio-demographic - gender

 Male

1.2 (0.882–1.634)

0.246

1.225 (0.896–1.675)

0.203

3.244 (1.864–5.644)

< 0.001***

3.238 (1.859–5.639)

< 0.001***

 Female

1.00

–

1.00

–

1.00

–

1.00

–

B. Lifestyle factors

Paternal Smoker

 Yes

1.00

–

1.00

–

1.00

–

1.00

–

 No

1.353 (0.956–1.912)

0.088

1.420 (1.001–2.016)

0.049*

0.901 (0.499–1.626)

0.728

0.919 (0.505–1.675)

0.784

Maternal Smoker

 Yes

1.00

–

1.00

–

1.00

–

1.00

–

 No

0.561 (0.163–1.933)

0.36

0.582 (0.167–2.03)

0.396

0.305 (0.083–1.126)

0.075

0.210 (0.054–0.813)

0.024*

Parental Smoking

 None

1.375 (0.972–1.944)

0.072

1.450 (1.022–2.058)

0.038*

0.956 (0.509–1.795)

0.888

0.912 (0.480–1.733)

0.780

 At least 1

1.00

–

1.00

–

1.00

–

1.00

–

Household smokers

 None

1.449 (1.030–2.039)

0.033*

1.529 (1.083–2.159)

0.016*

0.980 (0.542–1.775)

0.948

0.985 (0.539–1.801)

0.962

 At least 1

1.00

–

1.00

–

1.00

–

1.00

–

Alcohol drinking

 Non-drinker

1.00

–

1.00

–

1.00

–

1.00

–

 Drinker

1.183 (0.877–1.596)

0.272

1.218 (0.895–1.657)

0.209

1.821 (1.032–3.215)

0.039*

1.555 (0.869–2.786)

0.137

C. Familial history

Parental Acne

 None

1.00

–

1.00

–

1.00

–

1.00

–

 Only 1 parent

0.824 (0.506–1.341)

0.436

0.872 (0.531–1.432)

0.587

3.049 (1.346–6.944)

0.008**

3.817 (1.634–8.929)

0.002**

 Both

1.101 (0.718–1.689)

0.659

1.195 (0.773–1.847)

0.423

1.572 (0.687–3.597)

0.284

1.515 (0.653–3.521)

0.333

D. Co-morbidities

BMI

 18.5–23

1.00

–

1.00

–

1.00

–

1.00

–

  < 18.5

1.099 (0.721–1.675)

0.659

1.146 (0.748–1.755)

0.531

2.404 (1.185–4.878)

0.015*

2.445 (1.186–5.051)

0.015*

  > 23

1.061 (0.754–1.494)

0.735

0.957 (0.674–1.36)

0.808

1.381 (0.731–2.611)

0.320

1.241 (0.648–2.375)

0.515

Asthma

 Yes

0.631 (0.313–1.27)

0.197

0.544 (0.263–1.128)

0.102

4.359 (1.107–17.172)

0.035*

2.945 (0.689–12.588)

0.145

 No

1.00

–

1.00

–

1.00

–

1.00

–

E. Dietary habits

Nuts

 Never/ occasionally

1.00

–

1.00

–

1.00

–

1.00

–

 Once or twice/week

0.562 (0.384–0.824)

0.003**

0.585 (0.396–0.864)

0.007**

0.808 (0.404–1.618)

0.547

0.659 (0.322–1.346)

0.252

 Most or all days

0.524 (0.268–1.022)

0.058

0.547 (0.278–1.076)

0.081

0.646 (0.186–2.247)

0.492

0.692 (0.195–2.451)

0.569

Burgers/fast food

 Never/ occasionally

1.00

–

1.00

–

1.00

–

1.00

–

 Once or twice/week

0.637 (0.464–0.875)

0.005**

0.603 (0.436–0.834)

0.002**

0.746 (0.425–1.309)

0.307

0.660 (0.371–1.174)

0.157

 Most or all days

0.876 (0.500–1.534)

0.642

0.836 (0.473–1.477)

0.537

0.726 (0.243–2.174)

0.567

0.745 (0.245–2.262)

0.604

Cereal

 Never/ occasionally

1.00

–

1.00

–

1.00

–

1.00

–

 Once or twice/week

1.022 (0.587–1.781)

0.938

0.943 (0.537–1.655)

0.838

0.536 (0.231–1.244)

0.146

0.437 (0.183–1.046)

0.063

 Most or all days

1.005 (0.569–1.776)

0.986

0.956 (0.537–1.701)

0.877

0.303 (0.117–0.788)

0.014*

0.278 (0.105–0.739)

0.010*

Butter

 Never/ occasionally

1.00

–

1.00

–

1.00

–

1.00

–

 More than once/week

0.858 (0.599–1.229)

0.403

0.835 (0.578–1.205)

0.335

0.504 (0.260–0.975)

0.042*

0.451 (0.230–0.887)

0.021*

Milk

 Never/ occasionally

1.00

–

1.00

–

1.00

–

1.00

–

 Once or twice/week

1.33 (0.946–1.869)

0.101

1.294 (0.916–1.828)

0.144

0.457 (0.255–0.816)

0.008**

0.441 (0.244–0.797)

0.007**

 Most or all days

1.095 (0.724–1.655)

0.667

1.111 (0.731–1.69)

0.622

0.232 (0.088–0.609)

0.003**

0.259 (0.097–0.689)

0.007**

  1. Results are from univariate and multivariate analysis on the variables associated with moderate/severe acne with reference to mild acne, or acne cases with Grade 3/4 scarring with reference to acne cases with Grade 1/2 scarring
  2. Values are odds ratio (95% CI); *p < 0.05 ** p < 0.01 *** p < 0.001
  3. aAdjusted for age and gender