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Table 2 Sociodemographic and clinical characteristics by BMI trajectory groups (N = 264,230)

From: Long-term body mass index changes in overweight and obese adults and the risk of heart failure, cardiovascular disease and mortality: a cohort study of over 260,000 adults in the UK

 

Trajectory 1

(overweight-S) (n = 95,944)

Trajectory 2

(Obese 1-S) (n = 104,616)

Trajectory 3

(obese 2-S)

(n = 50,866)

Trajectory 4

(obese 3-S)

(n = 12,804)

Patient characteristics (Sociodemographic characteristics)

Age at start of study (mean (SD))

49.5 (13.2)

49.9 (12.7)

49.1 (12.2)

48.8 (11.2)

Male gender n (%)

37,882 (39.5)

41,685 (39.9)

16,652 (32.7)

3371 (26.3)

Smoking

 Ex-smoker

27,950 (29.1)

31,763 (30.4)

15,123 (29.7)

3703 (28.9)

 Light smoker (1–9 cigs/day)

6918 (7.2)

7071 (6.8)

3270 (6.4)

794 (6.2)

 Moderate smoker (10–19 cigs/day)

5118 (5.3)

5214 (5.0)

2347 (4.6)

503 (3.9)

 Heavy smoker (20–39 cigs/day)

3827 (4.0)

4470 (4.3)

2297 (4.5)

619 (4.8)

 Non-smoker

52,070 (54.3)

55,989 (53.5)

27,757 (54.6)

7153 (55.9)

Missing

61 (0.1)

109 (0.1)

72 (0.1)

32 (0.3)

Alcohol consumption

 Trivial (<  1 unit/day)

31,978 (33.3)

35,035 (33.5)

17,192 (33.8)

4203 (32.8)

 Light (1–2 units/day)

16,405 (17.1)

15,773 (15.1)

6133 (12.1)

1112 (8.7)

 Moderate (3–6 units/day)

9746 (10.2)

8748 (8.4)

3314 (6.5)

586 (4.6)

 Heavy (7–9 units/day)

2883 (3.0)

2961 (2.8)

1076 (2.1)

170 (1.3)

 Very heavy (> 9 units/day)

1621 (1.7)

1905 (1.8)

722 (1.4)

129 (1.0)

 Ex-alcohol consumption

3086 (3.2)

3759 (3.6)

2174 (4.3)

641 (5.0)

 No alcohol consumption

28,076 (29.3)

33,168 (31.7)

18,113 (35.6)

5341 (41.7)

Missing

2149 (2.2)

3267 (3.1)

2142 (4.2)

622 (4.9)

Deprivation (IMD quintile)

 1 (least deprived)

10,122 (10.6)

10,251 (9.8)

4334 (8.5)

827 (6.5)

 2

11,043 (11.5)

12,124 (11.6)

5549 (10.9)

1242 (9.7)

 3

9644 (10.1)

11,386 (10.9)

5654 (11.1)

1386 (10.8)

 4

9889 (10.3)

12,173 (11.6)

6412 (12.6)

1693 (13.2)

 5 (most deprived)

7528 (7.9)

9818 (9.4)

5799 (11.4)

1766 (13.8)

Missing records

47,718 (49.7)

48,864 (46.7)

23,118 (45.5)

5890 (46.0)

Weight profile and clinical characteristics

 Body mass index in kg/m2 (mean (SD))

  Baseline BMI

28.7 (2.2)

33.7 (2.7)

39.9 (3.5)

49.1 (5.7)

  BMI at 2 years

28.6 (2.2)

33.7 (2.4)

39.9 (3.2)

49.1 (5.4)

  BMI at 5 years

29.2 (2.3)

34.5 (2.4)

40.8 (3.1)

50.0 (5.3)

  BMI at 8 years

29.5 (2.5)

34.8 (2.6)

41.1 (3.3)

50.1 (5.4)

  BMI at 10 years

29.7 (2.8)

34.9 (3.0)

41.1 (3.7)

49.8 (5.7)

  Mean BMI change over 10 years

1.0 (3.1)

1.2 (3.7)

1.0 (4.6)

0.6 (6.3)

 Prevalence of comorbidities at baseline

  Atrial fibrillation

671 (0.7)

865 (0.8)

452 (0.9)

156 (1.2)

  Chronic kidney disease

771 (0.8)

998 (1.0)

532 (1.0)

159 (1.2)

  Hypertension

15,708 (16.4)

21,438 (20.5)

12,009 (23.6)

3419 (26.7)

  Type-2 diabetes

6384 (6.7)

8930 (8.5)

5609 (11.0)

1921 (15.0)

  Rheum arthritis/inflammatory diseases

1674 (1.7)

1970 (1.9)

952 (1.9)

261 (2.0)