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Table 3 Sensitivity analyses of lab-confirmed and epi-linked cases, and age-specific vaccine effectiveness. Borno, December 2018 – March, 2019

From: Measles outbreak in complex emergency: estimating vaccine effectiveness and evaluation of the vaccination campaign in Borno State, Nigeria, 2019

Original VE

Sensitivity analyses

VE for lab-confirmed cases

VE for epi-linked cases

Age Group

VE% (95% CI)

Vaccinated cases

Confirmeda cases

PCV (95% CI)

VE% (95% CI)

Vaccinated cases

Confirmeda cases

PCV (95% CI)

VE% (95% CI)

<  9 mob

0

2

0.00 (0.00–0.84)

1

47

0.02 (0.00–0.11)

9–11 mo

87.3 (71.0–95.2)

1

3

0.33 (0.01–0.91)

68.3 (−509–99.5)

6

39

0.15 (0.06–0.31)

88.5 (72.1–96.1)

12–23 mo

96.2 (92.6–98.3)

1

12

0.08 (0.00–0.38)

95.9 (71.5–99.9)

8

106

0.08 (0.03–0.14)

96.3 (92.4–98.4)

24–35 mo

97.3 (95.1–98.7)

0

11

0.00 (0.00–0.28)

100.0 (92.4–100.0)

12

86

0.14 (0.07–0.23)

96.9 (94.3–98.5)

36–47 mo

98.6 (96.7–99.6)

0

7

0.00 (0.00–0.41)

100.0 (86.8–100.0)

5

68

0.07 (0.02–0.16)

98.5 (96.3–99.5)

48–59 mo

89.2 (77.9–95.2)

1

8

0.13 (0.00–0.51)

94.0 (53.0–99.9)

9

41

0.22 (0.11–0.38)

88.1 (74.5–95.0)

60–71 mo

99.5 (98.3–99.9)

0

7

0.00 (0.00–0.41)

100.0 (95.6–100.0)

3

31

0.10 (0.02–0.26)

99.3 (97.8–99.9)

Overall

98.4 (97.8–98.8)

3

50

0.06 (0.01–0.17)

99.1 (97.2–99.8)

44

418

0.11 (0.08–0.14)

98.3

(97.7–98.8)

  1. Mo month, PCV Proportion of cases vaccinated, PP Proportion of the population vaccinated based on 2018 PCCS report, VE Vaccine effectiveness, CI Confidence Interval
  2. aCases reported from IDP camps were excluded from the VE estimation as the PCCS did not capture coverage from IDP camps
  3. bThe < 9 months’ infants were not scheduled for measles vaccination and were excluded from the VE estimation