ESTIMATE | PROBABILITY (%) or VALUE (RANGE) | REFERENCE |
---|---|---|
Probabilities (once-time percentages) | ||
Probability of completing latent TB infection treatment among those who initiate treatment | 75.6 | [28] |
Probability of diagnosing active disease | 90 | Assumption |
Probability of spontaneous resolution of untreated TB disease | 25 | [29] |
Probability of relapse after active TB treatment | 1.4 | Dynamic modelb,d |
Protective immunity from previous TB disease | 55 | Dynamic modelb |
Probabilities for those without any of the four specific TB risk factors | ||
Probability of rapid progression following TB infection | 0.18/yeara | Dynamic modelb |
Probability of reactivation of longstanding latent TB infection to TB disease | 0.05/year | |
Probability of dying from untreated TB | 7.7/yearc | [33] |
Probability of dying from TB during treatment | 1.7/yearc | [34] |
Quality Adjusted Life Years for Latent TB Iinfectuin and active TB | ||
Utility score for individual with active TB disease (during treatment) | 0.85 (0.70–0.90) | [35] |
Utility score for individual with active TB disease (before treatment) | 0.68 (0.65–0.72) | [36] |
Utility score for individual with latent TB infection, (during treatment) | 0.97 (0.95–1.00) | [36] |
Utility score for individual with latent TB infection (before treatment) | 1 | Assumptione |