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Table 2 Sensitivity and specificity of various definitions of retention in care among B+ HIV+ pregnant women defined as alive and retained in care according to the ‘point’ retention definition (n = 16,840)

From: Measuring retention in care for HIV-positive pregnant women in Prevention of Mother-to-Child Transmission of HIV (PMTCT) option B+ programs: the Mozambique experience

Retained in care according to type of definition (n = 16,840)Alive and retained in care with ≥75% of visits in time (Reference)Sensitivity 95% CISpecificity 95% CI% of misclassification
YesNo
‘Point’ retention40716,43397.6%
WHO40513,1543.0% [2.7–3.3%]99.9% [99.8–100%]78.1%
MOH40790934.3% [3.9–4.7%]100% [99.9–100%]54.0%
IATT24925159.0% [8.0–10.1%]98.9% [98.7–99.0%]15.9%
‘Appointment adherence’ retention407307611.7% [10.6–12.8%]100% [100–100%]18.3%
  1. The ‘on-time adherence’ definition of retention is considered as the reference (n = 407 women retained in care at 12-months post-ART initiation and with ≥75% on-time adherence to scheduled visits). The percentage of misclassified patients is calculated using the sum of patients incorrectly classified according to each definition divided by the total number of patients included in the analysis
  2. CI confidence interval, IATT Inter-Agency Task Team, MOH Ministry of Health, WHO World Health Organization