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Table 1 Overall and age-sex-specific annual prevalence rate of lower-extremity amputation from 2009 to 2013

From: Urban-rural disparity in lower extremities amputation in patients with diabetes after nearly two decades of universal health Insurance in Taiwan

 Year
20092010201120122013Change %βP for trend
No. of patientsa662,877718,995751,845809,502899,412   
 Case numberb20161988181015781844   
 Female914873803643730   
 Male1102111510079351114   
Prevalence rate (104)
 Overall30.4 (29.1–31.7)27.6 (26.4–28.9)24.1(23–25.2)19.5 (18.5–20.5)20.5 (19.6–21.4) −0.114< 0.001
Female
  55–64 years17.2 (14.8–19.5)16.0 (13.8–18.2)12.8 (10.9–14.6)10.0 (8.4–11.6)9.6 (8.1–11.1)−44%−0.164< 0.001
  65–74 years24.4 (21.7–27.2)19.9 (17.5–22.3)19.7 (17.3–22.1)14.1 (12.2–16.1)15.4 (13.5–17.4)−37%−0.127< 0.001
  75–84 years34.4 (30.4–38.3)32.1 (28.4–35.7)28.9 (25.4–32.3)21.2 (18.4–24.1)20.8 (18.2–23.4)−39%−0.140< 0.001
  85 years and over59.0 (48.1–70.0)48.8 (39.6–58.1)38.5 (30.3–46.8)29.1 (22.4–35.8)30.0 (24.0–36.0)−49%− 0.186< 0.001
  All females26.3 (24.6–28.0)23.2 (21.7–24.8)20.5 (19.0–21.9)15.2 (14.1–16.4)15.7 (14.5–16.8)−40%− 0.145< 0.001
Male
 55–64 years28.9 (25.9–31.8)24.7 (22.1–27.3)23.4 (21.0–25.7)23.0 (20.7–25.2)21.3 (19.2–23.4)−26%−0.068< 0.001
 65–74 years35.6 (32.0–39.3)35.6 (32.0–39.2)27.9 (24.8–31.0)23.3 (20.6–26.0)25.0 (22.3–27.7)−30%−0.113< 0.001
 75–84 years41.1 (36.4–45.8)42.3 (37.7–47.0)37.3 (32.9–41.7)25.7 (22.1–29.3)32.9 (29.0–36.7)−20%−0.091< 0.001
 85 years and over52.0 (40.5–63.6)34.7 (26.0–43.4)31.8 (23.5–40.1)32.3 (24.6–40.1)37.3 (29.9–44.6)−28%−0.0670.068
 All males34.9 (32.9–37.0)32.5 (30.6–34.4)28.0 (26.3–29.8)24.1 (22.6–25.7)25.7 (24.2–27.2)−26%−0.091< 0.001
  1. Interaction term of year and gender = 0.055 (p < 0.001)
  2. Interaction terms of year and age = − 0.011 (p = 0.139)
  3. Numbers in parentheses are 95% confidence intervals
  4. a Number of patients with diabetes b Number of patients with diabetes received amputations
  5. β is the year trend of annual prevalence rate of LEA between 2009 and 2013 estimated from Poisson regression model