Table 1 ICER (USD at 2018 price levels) (Assuming 25% of non-UAI get PrEP of whom 75% of stop using condoms)
From: Cost utility analysis of HIV pre exposure prophylaxis among men who have sex with men in Israel
Without PrEP | With PrEP | Change | |
|---|---|---|---|
Assuming four years background decrease in HIV incidence of 5.2% | |||
HIV cases | 1113 | 621 | −493 |
DALY losses | 3651 | 2035 | −1616 |
Extra Costs or Savings (−) | |||
Costs | |||
Intervention | – | 1,897,994,185 | 1,897,994,185 |
Treatment Costs | 574,205,146 | 320,086,559 | −254,118,587 |
Productivity Losses | 176,601,307 | 98,445,173 | −78,156,144 |
Premature Burial | 4,796,748 | 2,673,913 | −2,122,835 |
TOTAL | 755,603,201 | 2,319,199,820 | 1,563,596,619 |
Incremental Cost-Effectiveness Ratio (USD per DALY) | 967,744 | ||
Assuming eight years background decrease in HIV of 5.2% | |||
HIV Cases | 1037 | 578 | − 459 |
DALY losses | 3422 | 1908 | − 1515 |
Extra Costs or Savings (−) | |||
Total Costs | 708,287,160 | 2,292,823,802 | 1,583,536,642 |
Incremental Cost-Effectiveness Ratio (USD per DALY) | 1,046,219 | ||
Assuming no further background decrease in HIV | |||
HIV Cases | 1308 | 729 | − 579 |
DALY losses | 4264 | 2377 | − 1887 |
Extra Costs or Savings (−) | |||
Total Costs | 882,406,479 | 2,389,885,374 | 1,507,478,895 |
Incremental Cost-Effectiveness Ratio (USD per DALY) | 798,876 | ||