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Table 1 Summary of systematic reviews conducted on antenatal depression included in this systematic review of reviews (N = 10)

From: Global burden of antenatal depression and its association with adverse birth outcomes: an umbrella review

Review

Geographic coverage of the review

Prominent tools used

Data base searched

Number of primary studies

Number of participants

Quality assessment

Main findings relevant to the review

AMSTAR score

Antenatal depression Prevalence

Risk factors

Biaggie, 2016

From 2003 to 2015

Developed countries

Not reported

PubMed, Psych INFO, Cochrane Library

97

1,541,303

Not assessed

Not reported

- Lack of partner or social support (in 13 studies);

- History of abuse or domestic violence (in 6 studies);

- Personal history of mental illness (in 7 studies);

- Un-planned or unwanted pregnancy (in 4 studies);

- Adverse events in life and high perceived stress (in 3 studies);

- Present or past pregnancy complications or loss (in 3 studies)

5

Gelaye et al., 2016

From 1998 to 2015

Low and middle-income countries

EPDS (22 studies)

PubMed, Embase, CINAHL, BIOSIS Online

51

48,904

Not assessed quality of the primary studies

25.3% (95% CI 21.4–29.6%)

- Early life abuse (child maltreatment, a severe early life stressor, includes all forms of physical, sexual and psychological maltreatment that pose harm to a child’s health, development or dignity) in 2 studies

- Adult abuse (intimate partner violence (IPV), encompassing physical, psychological and sexual abuse in five studies

- Maternal low educational attainment in two studies

- Maternal current low economic status in three studies

- Lack of social support in one study

- History of mental illness in one study

7

Halim et al. 2017

From 1990 to 2017

Low and Lower middle-income countries

EPDS in ten studies

PubMed, Web of Science, Scopus, Psyc Info, Applied Social Science Index and Abstracts (ASSIA)

24

13,490

Quality assessed but not used standard criteria

15—65%

- Intimate partner violence during pregnancy in 24 studies

7

Mitchel et al. 2017

From 1980 to 2015

Developed countries

BDI in six studies

PubMed, MEDLINE, Embase and PsychINFO

12

4751

NOS criteria

Not reported

- Hyperemesis gravidarum in 12 studies

7

Roomruangwong C et al. 2011

From 1968 to 2010

Asian countries

BDI in six studies

MEDLINE (PubMed), PsychINFO and SCOPUS

25

9126

Not assessed the quality of primary studies

20%

- Having a history of premenstrual symptoms (in 3 studies)

- Poor marital relationship (in 3 studies)

- Unplanned/unwanted pregnancy especially, during premarital period (in 8 studies)

- Poor obstetric history (complication before or in current pregnancy) in five studies

- Financial difficulties (in 4 studies)

- Lack of support from husband or relatives (in 7 studies)

4

Sparling et al. 2017

From 2008 to 2015

All studies are included from developed countries except one from India

EPDS in 21 studies

PubMed, EMBASE and CINAHL

35

88,051

Quality in Prognostic Studies tool, Cochrane Collaboration tool

Not reported

- 173 studies, including three polyunsaturated fatty acids (PUFA) supplementation trials, found no evidence of an association between polyunsaturated fatty acid and depression)

- 22 studies showed protective effects of healthy dietary patterns, multivitamin supplementation, fish and PUFA intake, calcium, vitamin D, zinc and possibly selenium from depression.

- Given the methodological limitations of existing studies and inconsistencies in findings across studies, the evidence on whether nutritional factors influence the risk of perinatal depression is still inconclusive.

7

Underwood et al. 2016

From 2000 to 2015

Developed countries

EPDS in 13 studies

Embase, PsychINFO, MEDLINE and Cochrane Reviews

16

35,419

List of criteria’s that could resemble the standard quality assessment tool

17%

- Previous depression history was found as a predictor of a current depression during pregnancy in five studies

7

Wosu Ac et al. 2015

From 1999 to 2014

Majority were from USA but the rest were from other developed countries

CES-D/ in three studies

PubMed, EMBASE, PyscINFO, CINAHL, Web of Science, BIOSIS, and Science Direct

7

2161

Newcastle-Ottawa Scale (NOS)

Not reported

- Childhood sexual abuse is strongly associated with prenatal depression (six studies)

8

Lancaster CA et al. 2010

From 1980 to 2008

Developed countries

CES- D in 49 studies

PubMed, CINAHL, SCOPUS, PsycINFO, Sociological Abstracts, ISI Proceedings, ProQuest

57

36,257

Quality assessment tool adapted from methods of the US Preventive Services Task Force

Not reported

- Life stress (in 18 studies),

- lack of social support (in 24 studies),

- Domestic violence (in seven studies)

- Unwanted pregnancy (in six studies)

- Lowe income (in 11 studies)

- Unemployment (in 14 studies)

- Lower education (in 20 studies)

- Smoking (in 11 studies)

- Alcohol use (in 10 studies)

- Illicit drug use (in 8 studies)

- Nulliparity (in 18 studies)

- Poor obstetric history (in 10 studies)

7

Howard LM et al. 2013

From 2000 to 2012

From all continent except Africa

EPDS in 35 studies

Medline, Embase, and PsycINFO, and hand searches of Trauma Violence and Abuse, Journal of Traumatic Stress, and Violence Against Women

67

171,465

Yes, quality appraisal checklist

Not reported

- Life time domestic violence (in 11 studies) with a pooled odds ratio and 95%CI [3.04: 2.31,4.01, I2 = 51.1%]

- Any past year partner violence in five studies, Pooled odds ratio with 95%CI [2.82: 1.52, 5.28, I2 = 75.3%]

- Partner violence during pregnancy in seven studies, Pooled odds ratio with 95%CI [5.00: 4.94, 6.17, I2 = 23.7%]

8