Table 1 Clinical and biochemical characteristics between the study groups before and after intervention
From: Effect of a family and interdisciplinary intervention to prevent T2D: randomized clinical trial
Anthropometric Characteristics | Individual Group (n = 65) | Familiar Group (n = 57) | ||||
|---|---|---|---|---|---|---|
Basal (n = 65) | Month 6 (n = 48) | Month 12 (n = 39) | Basal (n = 57) | Month 6 (n = 42) | Month 12 (n = 32) | |
Weight (kg) | 81.8 ± 17.0 | 75.4 ± 17.5B | 76.7 ± 19.8 C | 82.1 ± 18.0 | 78.5 ± 19.0 E | 76.2 ± 15.0 F |
BMI (kg/m2) | 30.2 ± 5.3 | 28.3 ± 5.5B | 28.9 ± 6.5 C | 30.3 ± 5.8 | 29.2 ± 6.0 E | 28.6 ± 4.6F |
WC (cm) | 95.3 ± 12.0 | 91.5 ± 12.4 B | 93.5 ± 13.5 | 96.2 ± 14.0 | 92.8 ± 17.4 | 92.8 ± 10.5 |
Body fat (%) | 34.8 ± 8.3 | 32.7 ± 8.8 B | 35.6 ± 7.6 | 34.8 ± 8.3 | 33.6 ± 9.0 E | 34.5 ± 9.0 |
Visceral Index (AU) | 11.0 ± 4.8 | 9.8 ± 4.6B | 11.3 ± 4.9 | 11.3 ± 4.6 | 11.0 ± 4.7 E | 10.6 ± 4.3 F |
SBP (mm Hg) | 123 ± 16 | 119 ± 16.7 | 121 ± 14 | 116 ± 11 | 113 ± 12 | 122 ± 15 |
Biochemistry Characteristics | ||||||
Glucose (mg/dl) 0 min | 101 ± 10 | 97 ± 10B | 94 ± 10C | 104 ± 9 | 97 ± 11 E | 98 ± 8 F |
Glucose (mg/dl) 120 min | 146 ± 23 | 131 ± 45B | 127 ± 33C | 149 ± 27 | 135 ± 35E | 142 ± 33 |
HbA1c (%) | 5.3 ± 0.5 | 5.4 ± 0.3 | 5.4 ± 0.3 | 5.1 ± 0.7 | 5.5 ± 0.4E | 5.4 ± 0.3 F |
AUCgluc_OGTT (mg/dl/120 min) | 18,398 ± 2403 | 17,749 ± 3965 | 17,204 ± 3429 | 18,597 ± 2611 | 17,637 ± 3849E | 17,237 ± 2792F |
Tg (mg/dl) | 159 ± 79 | 135 ± 58 | 148 ± 58 | 192 ± 90 | 167 ± 79 | 210 ± 164 |
Total Cholesterol (mg/dl) | 181 ± 34 | 177 ± 35∆H | 183 ± 35∆I | 197 ± 40 | 186 ± 38E, ∆H | 186 ± 35F∆I |
HDL (mg/dl) | 40 ± 11 | 44 ± 13 | 39 ± 14 | 42 ± 11 | 44 ± 16 | 44 ± 12 |
LDL (mg/dl) | 112 ± 33 | 108 ± 27 | 118 ± 32∆I | 121 ± 36 | 108 ± 33E | 106 ± 38F, ∆I |
Markers of insulin resistance and pancreatic β-cell function | ||||||
Matsuda Index | 3.9 ± 1.9 | 4.8 ± 2.6B | 4.9 ± 3.0C | 3.5 ± 2.3 | 4.9 ± 3.5E | 4.7 ± 3.5F |
HOMA IR | 2.9 ± 2.0 | 2.4 ± 1.9B | 2.4 ± 1.7C | 3.5 ± 2.0 | 2.9 ± 3.4 | 3.1 ± 2.7 |
Insulin secretion | 0.45 ± 0.20 | 0.44 ± 0.22 | 0.49 ± 0.25∆I | 0.58 ± 0.38 | 0.48 ± 0.26 | 0.50 ± 0.27∆I |
Disposition Index | 1.5 ± 0.4 | 1.8 ± 0.7B | 1.9 ± 0.7C∆I | 1.5 ± 0.5 | 1.9 ± 0.9E | 1.7 ± 0.5∆I |
Oral Disposition Index | 0.11 ± 0.12 | 0.15 ± 0.18 | 0.08 ± 0.14 | 0.13 ± 0.13 | 0.11 ± 0.12 | 0.11 ± 0.06 |