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Table 1 Characteristics of the study population (1999-2018)

From: Everything counts - a method to determine viral suppression among people living with HIV using longitudinal data for the HIV care continuum - results of two large, German, multi-center real-life cohort studies over 20 years (1999–2018)

 

Patients

Study population

(all diagnosed PLHIV)

People who initiated ART

24,569

(100%)

22,120

(100%)

Observation time

Total PY

171,990

 

164,691

 

Sex

Male

19,794

(81%)

17,794

(80%)

Female

4775

(19%)

4326

(20%)

HIV transmission risk

Men who have sex with men (MSM)

13,006

(53%)

11,676

(53%)

Heterosexual contacts

3227

(13%)

2954

(13%)

High prevalence country

3200

(13%)

2958

(13%)

People with injecting drug use

1612

(7%)

1411

(6%)

Other

212

(1%)

203

(1%)

Unknown

3312

(13%)

2918

(13%)

Region of origin

Germany

16,683

(68%)

15,065

(68%)

Eastern Europe

682

(3%)

592

(3%)

Central Europe

1129

(5%)

1021

(5%)

Western Europe

(excl. Germany)

949

(4%)

834

(4%)

Africa

2998

(12%)

2749

(12%)

Asia

686

(3%)

649

(3%)

America

546

(2%)

491

(2%)

Caribbean/Ozeania

107

(0%)

96

(0%)

Unknown

789

(3%)

623

(3%)

Age at Enrolment (years)

Median (IQR)

37

(30-45)

37

(31-45)

Enrollment

1999–2001

3422

(14%)

3098

(14%)

2002–2005

5454

(22%)

4834

(22%)

2006–2009

5529

(23%)

4925

(22%)

2010–2013

5343

(22%)

4819

(22%)

2014–2018

4821

(20%)

4444

(20%)

Observation time (years)

Median (IQR)

5.9

(2.4-11)

6.5

(2.8-11.5)

Number of viral loads

Median (IQR)

18

(7-35)

17

(8-32)

Distance between viral loads (days)

Median (IQR)

91

(64–112)

91

(70–112)

Viral load

baseline (copies/ml)

Median (IQR)

49,973

(9350–198,000)

55,544

(10,899–211,000)

CD4 cell count

baseline (cells/μl)

Median (IQR)

349

(174–537)

328

(157–513)

Initiated ART

N (%)

22,120

(90%)

  

ART start period

1999–2001

  

2416

(11%)

2002–2005

  

3948

(18%)

2006–2009

  

4833

(22%)

2010–2013

  

5636

(25%)

2014–2018

  

5287

(24%)

not started ART

  

2449

(11%)

Age at ART start (years)

Median (IQR)

  

39

(32-46)

Time between enrollment and ART (days)

Mean (IQR)

  

321

(0–237)

Viral load

ART start (copies/ml)

Median (IQR)

  

62,000

(12,300-212,604)

CD4 cell count

ART start (cells/μl)

Median (IQR)

  

271

(133–429)

ART duration (years)

Median (IQR)

  

5.5

(2.3-9.9)