Characteristics of paediatric patients with tuberculosis and associated determinants of treatment success in Malaysia using the MyTB version 2.1 database over five years

Table 4 Multivariable logistic regression for the determinants of treatment success among children with TB in Malaysia, 2013–2017

Parameters	Crude OR	95% CI		Model 1 aOR	95% CI		P- value	Model 2 ^aaOR (MICE)	95% CI		P-value
	Crude OR	Lower	Upper	Model 1 aOR	Lower	Upper		Model 2 ^aaOR (MICE)	Lower	Upper
Socio-demographic profiles
Age	1.06	1.04	1.09	1.05	1.03	1.08	< 0.001	1.06	1.03	1.09	< 0.001
Sex
Male	ref	–	–	–	–	–	–	–	–	–	–
Female	1.23	0.99	1.53	1.00	0.77	1.30	0.987	1.11	0.88	1.41	0.384
Citizenship
Malaysian	5.39	4.23	6.85	4.21	2.89	6.11	< 0.001	3.43	2.47	4.75	< 0.001
Non-Malaysian	ref	–	–	ref	–	–	–	ref	–	–	–
Place of residence
Urban	1.14	0.91	1.42	0.91	0.70	1.18	0.485	0.93	0.73	1.19	0.563
Rural	ref	–	–	–	–	–	–	–	–	–	–
Treatment centre one
Public hospital	0.43	0.29	0.63	0.37	0.21	0.61	< 0.001	0.38	0.25	0.58	< 0.001
Public clinic	ref	–	–	–	–	–	–	ref	–	–	–
Private facilities	0.87	0.43	1.91	0.78	0.34	1.94	0.581	0.79	0.36	1.71	0.544
TB disease profile
BCG scar
Yes	4.85	3.8	6.17	1.88	1.28	2.72	0.00102	1.93	1.39	2.68	< 0.001
No	ref	–	–	ref	–	–		ref	–	–
CXR finding
No lesion	ref	–	–	ref	–	–		ref	–	–
Minimal	1.11	0.83	1.49	0.97	0.66	1.41	0.868	1.01	0.70	1.44	0.976
Advanced	0.46	0.34	0.63	0.48	0.32	0.71	< 0.001	0.48	0.33	0.69	< 0.001
HIV co-infection
Yes	0.29	0.16	0.57	0.27	0.13	0.58	< 0.001	0.31	0.16	0.63	0.001
No	ref	–	–	ref	–	–		ref	–	–
Type of TB
PTB SS -ve	ref	–	–	ref	–	–		ref	–	–
PTB SS + ve	0.66	0.51	0.86	0.62	0.44	0.86	0.004	0.58	0.43	0.79	< 0.001
EPTB	0.76	0.58	0.99	0.55	0.38	0.80	0.002	0.58	0.41	0.82	0.002

Summary of model fit for Model 1:
Hosmer-Lemeshow goodness of fit: p-value = 0.1108
Likelihood ratio test: p-value < 0.001
Classification table: 90.6%
Area under the curve: 0.73 (95% CI: 0.70–0.77)
Akaike information criterion: 1729.1
^aaOR MICE: Adjusted odds ratio with multivariate imputation by chained equations

ISSN: 1471-2458