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Table 4 Multivariable logistic regression for the determinants of treatment success among children with TB in Malaysia, 2013–2017

From: Characteristics of paediatric patients with tuberculosis and associated determinants of treatment success in Malaysia using the MyTB version 2.1 database over five years

Parameters Crude OR 95% CI Model 1
aOR
95% CI P- value Model 2 aaOR
(MICE)
95% CI P-value
  Lower Upper Lower Upper   Lower Upper  
Socio-demographic profiles
 Age 1.06 1.04 1.09 1.05 1.03 1.08 < 0.001 1.06 1.03 1.09 < 0.001
 Sex
  Male ref
  Female 1.23 0.99 1.53 1.00 0.77 1.30 0.987 1.11 0.88 1.41 0.384
 Citizenship
  Malaysian 5.39 4.23 6.85 4.21 2.89 6.11 < 0.001 3.43 2.47 4.75 < 0.001
  Non-Malaysian ref ref ref
 Place of residence
  Urban 1.14 0.91 1.42 0.91 0.70 1.18 0.485 0.93 0.73 1.19 0.563
  Rural ref
 Treatment centre one
  Public hospital 0.43 0.29 0.63 0.37 0.21 0.61 < 0.001 0.38 0.25 0.58 < 0.001
  Public clinic ref ref
  Private facilities 0.87 0.43 1.91 0.78 0.34 1.94 0.581 0.79 0.36 1.71 0.544
TB disease profile
 BCG scar
  Yes 4.85 3.8 6.17 1.88 1.28 2.72 0.00102 1.93 1.39 2.68 < 0.001
  No ref ref   ref  
 CXR finding
  No lesion ref ref   ref  
  Minimal 1.11 0.83 1.49 0.97 0.66 1.41 0.868 1.01 0.70 1.44 0.976
  Advanced 0.46 0.34 0.63 0.48 0.32 0.71 < 0.001 0.48 0.33 0.69 < 0.001
 HIV co-infection
  Yes 0.29 0.16 0.57 0.27 0.13 0.58 < 0.001 0.31 0.16 0.63 0.001
  No ref ref   ref  
 Type of TB
  PTB SS -ve ref ref   ref  
  PTB SS + ve 0.66 0.51 0.86 0.62 0.44 0.86 0.004 0.58 0.43 0.79 < 0.001
  EPTB 0.76 0.58 0.99 0.55 0.38 0.80 0.002 0.58 0.41 0.82 0.002
  1. Summary of model fit for Model 1:
  2. Hosmer-Lemeshow goodness of fit: p-value = 0.1108
  3. Likelihood ratio test: p-value < 0.001
  4. Classification table: 90.6%
  5. Area under the curve: 0.73 (95% CI: 0.70–0.77)
  6. Akaike information criterion: 1729.1
  7. aaOR MICE: Adjusted odds ratio with multivariate imputation by chained equations